Extraskeletal Ewing sarcoma (EES) is a rare tumor diagnosed in children or young adults and is even more unusual in individuals over 30 years of age. Due to its rare occurrence and low index of suspicion, this tumor can pose diagnostic and therapeutic challenges. We present a case of a 60-year-old male with EES of the sciatic nerve, an unexpected entity given the patient's age, tumor type, and tumor location. This can mimic a nerve sheath tumor on imaging.
Keywords: EES, extraskeletal Ewing sarcoma; EFT, Ewing family of tumors; EWSR1, Ewing sarcoma RNA binding protein 1; Ewing sarcoma; Extraosseous Ewing sarcoma; Extraskeletal Ewing sarcoma; FISH, fluorescent in situ hybridization; LCA, leukocyte common antigen; PNET, primitive neuroectodermal tumor; Sciatic nerve.
© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.