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Opportunities for Ferroptosis in Cancer Therapy.
Fujihara KM, Zhang BZ, Clemons NJ. Fujihara KM, et al. Among authors: zhang bz. Antioxidants (Basel). 2021 Jun 21;10(6):986. doi: 10.3390/antiox10060986. Antioxidants (Basel). 2021. PMID: 34205617 Free PMC article.
Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction.
Fujihara KM, Zhang BZ, Jackson TD, Ogunkola MO, Nijagal B, Milne JV, Sallman DA, Ang CS, Nikolic I, Kearney CJ, Hogg SJ, Cabalag CS, Sutton VR, Watt S, Fujihara AT, Trapani JA, Simpson KJ, Stojanovski D, Leimkühler S, Haupt S, Phillips WA, Clemons NJ. Fujihara KM, et al. Among authors: zhang bz. Sci Adv. 2022 Sep 16;8(37):eabm9427. doi: 10.1126/sciadv.abm9427. Epub 2022 Sep 14. Sci Adv. 2022. PMID: 36103522 Free PMC article.