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Page 1
Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.
Clin Pharmacol Ther. 2023 Mar;113(3):712-723. doi: 10.1002/cpt.2846. Epub 2023 Jan 31.
Clin Pharmacol Ther. 2023.
PMID: 36629403
Prediction of Drug-Drug-Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling.
Kovar C, Kovar L, Rüdesheim S, Selzer D, Ganchev B, Kröner P, Igel S, Kerb R, Schaeffeler E, Mürdter TE, Schwab M, Lehr T.
Kovar C, et al. Among authors: ganchev b.
Pharmaceutics. 2022 Nov 25;14(12):2604. doi: 10.3390/pharmaceutics14122604.
Pharmaceutics. 2022.
PMID: 36559098
Free PMC article.
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A new [2H]-labelled α-trichloroimidate glucuronic ester for the synthesis of deuterated drug conjugates.
Heinkele G, Geditz MC, Ganchev B, Kerb R, Hofmann U, Mürdter TE.
Heinkele G, et al. Among authors: ganchev b.
J Labelled Comp Radiopharm. 2014 Oct;57(12):699-703. doi: 10.1002/jlcr.3243. Epub 2014 Oct 22.
J Labelled Comp Radiopharm. 2014.
PMID: 25339577
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Quantification of clomiphene metabolite isomers in human plasma by rapid-resolution liquid chromatography-electrospray ionization-tandem mass spectrometry.
Ganchev B, Heinkele G, Kerb R, Schwab M, Mürdter TE.
Ganchev B, et al.
Anal Bioanal Chem. 2011 Jul;400(10):3429-41. doi: 10.1007/s00216-011-5045-9. Epub 2011 May 1.
Anal Bioanal Chem. 2011.
PMID: 21533795
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Simultaneous quantitative analysis of letrozole, its carbinol metabolite, and carbinol glucuronide in human plasma by LC-MS/MS.
Precht JC, Ganchev B, Heinkele G, Brauch H, Schwab M, Mürdter TE.
Precht JC, et al. Among authors: ganchev b.
Anal Bioanal Chem. 2012 Apr;403(1):301-8. doi: 10.1007/s00216-012-5813-1. Epub 2012 Feb 25.
Anal Bioanal Chem. 2012.
PMID: 22367241
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Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites.
Mürdter TE, Kerb R, Turpeinen M, Schroth W, Ganchev B, Böhmer GM, Igel S, Schaeffeler E, Zanger U, Brauch H, Schwab M.
Mürdter TE, et al. Among authors: ganchev b.
Hum Mol Genet. 2012 Mar 1;21(5):1145-54. doi: 10.1093/hmg/ddr543. Epub 2011 Nov 22.
Hum Mol Genet. 2012.
PMID: 22108178
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