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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 1
2005 1
2006 4
2007 3
2008 2
2009 5
2010 11
2011 9
2012 11
2013 3
2014 4
2015 7
2016 10
2017 16
2018 7
2019 13
2020 13
2021 7
2022 5
2023 6
2024 3

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133 results

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Page 1
Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis.
Reichelt J, Sachs W, Frömbling S, Fehlert J, Studencka-Turski M, Betz A, Loreth D, Blume L, Witt S, Pohl S, Brand J, Czesla M, Knop J, Florea BI, Zielinski S, Sachs M, Hoxha E, Hermans-Borgmeyer I, Zahner G, Wiech T, Krüger E, Meyer-Schwesinger C. Reichelt J, et al. Among authors: florea bi. Nat Commun. 2023 Apr 13;14(1):2114. doi: 10.1038/s41467-023-37836-8. Nat Commun. 2023. PMID: 37055432 Free PMC article.
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence.
Jiang M, Huizenga MCW, Wirt JL, Paloczi J, Amedi A, van den Berg RJBHN, Benz J, Collin L, Deng H, Di X, Driever WF, Florea BI, Grether U, Janssen APA, Hankemeier T, Heitman LH, Lam TW, Mohr F, Pavlovic A, Ruf I, van den Hurk H, Stevens AF, van der Vliet D, van der Wel T, Wittwer MB, van Boeckel CAA, Pacher P, Hohmann AG, van der Stelt M. Jiang M, et al. Among authors: florea bi. Nat Commun. 2023 Dec 5;14(1):8039. doi: 10.1038/s41467-023-43606-3. Nat Commun. 2023. PMID: 38052772 Free PMC article.
The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration.
Sachs W, Blume L, Loreth D, Schebsdat L, Hatje F, Koehler S, Wedekind U, Sachs M, Zieliniski S, Brand J, Conze C, Florea BI, Heppner F, Krüger E, Rinschen MM, Kretz O, Thünauer R, Meyer-Schwesinger C. Sachs W, et al. Among authors: florea bi. Nat Commun. 2024 Mar 1;15(1):1897. doi: 10.1038/s41467-024-46273-0. Nat Commun. 2024. PMID: 38429282 Free PMC article.
Synthesis of broad-specificity activity-based probes for exo-β-mannosidases.
McGregor NGS, Kuo CL, Beenakker TJM, Wong CS, Offen WA, Armstrong Z, Florea BI, Codée JDC, Overkleeft HS, Aerts JMFG, Davies GJ. McGregor NGS, et al. Among authors: florea bi. Org Biomol Chem. 2022 Jan 26;20(4):877-886. doi: 10.1039/d1ob02287c. Org Biomol Chem. 2022. PMID: 35015006 Free PMC article.
Use of proteasome inhibitors.
Downey SL, Florea BI, Overkleeft HS, Kisselev AF. Downey SL, et al. Among authors: florea bi. Curr Protoc Immunol. 2015 Apr 1;109:9.10.1-9.10.8. doi: 10.1002/0471142735.im0910s109. Curr Protoc Immunol. 2015. PMID: 25845565
The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe.
Kuo CL, Su Q, van den Nieuwendijk AMCH, Beenakker TJM, Offen WA, Willems LI, Boot RG, Sarris AJ, Marques ARA, Codée JDC, van der Marel GA, Florea BI, Davies GJ, Overkleeft HS, Aerts JMFG. Kuo CL, et al. Among authors: florea bi. Org Biomol Chem. 2023 Oct 4;21(38):7813-7820. doi: 10.1039/d3ob01261a. Org Biomol Chem. 2023. PMID: 37724332
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA.
Bakker AT, Kotsogianni I, Mirenda L, Straub VM, Avalos M, van den Berg RJBHN, Florea BI, van Wezel GP, Janssen APA, Martin NI, van der Stelt M. Bakker AT, et al. Among authors: florea bi. J Am Chem Soc. 2023 Jan 18;145(2):1136-1143. doi: 10.1021/jacs.2c10819. Epub 2022 Dec 30. J Am Chem Soc. 2023. PMID: 36584241 Free PMC article.
133 results