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Page 1
Quantification of Global DNA Hydroxymethylation Level Using UHRF2 SRA-Luciferase Based on Bioluminescence Resonance Energy Transfer.
Taka N, Asami S, Sakamoto M, Matsui T, Yoshida W. Taka N, et al. Anal Chem. 2022 Jun 21;94(24):8618-8624. doi: 10.1021/acs.analchem.1c05619. Epub 2022 Jun 3. Anal Chem. 2022. PMID: 35657260

We demonstrated that the BRET signal between UHRF2 SRA-Fluc and BOBO-3 depends on the global hydroxymethylation level in the presence of MBD (R(2) = 0.99, and relative standard deviation < 2.3%). The limit of detection for hydroxymethylated genomic DNA was 0.75 ng

…
We demonstrated that the BRET signal between UHRF2 SRA-Fluc and BOBO-3 depends on the global hydroxymethylation level in the presence …
Infection Manager System (IMS) as a new hemocytometry-based bacteremia detection tool: A diagnostic accuracy study in a malaria-endemic area of Burkina Faso.
Post A, Kaboré B, Bognini J, Diallo S, Lompo P, Kam B, Herssens N, van Opzeeland F, van der Gaast-de Jongh CE, Langereis JD, de Jonge MI, Rahamat-Langendoen J, Bousema T, Wertheim H, Sauerwein RW, Tinto H, Jacobs J, de Mast Q, van der Ven AJ. Post A, et al. PLoS Negl Trop Dis. 2021 Mar 1;15(3):e0009187. doi: 10.1371/journal.pntd.0009187. eCollection 2021 Mar. PLoS Negl Trop Dis. 2021. PMID: 33647009 Free PMC article.
The overall sensitivity, specificity, and negative predictive value (NPV) of IMS for detection of bacteremia in patients of 5 years were 97.0% (95% CI: 89.8-99.6), 68.2% (95% CI: 55.6-79.1) and 95.7% (95% CI: 85.5-99.5) respectively, compared to 93.9% (95% CI: 85.2-98.3), 39.4% ( …
The overall sensitivity, specificity, and negative predictive value (NPV) of IMS for detection of bacteremia in patients of 5 years were 97. …
Investigating selected host and parasite factors potentially impacting upon seasonal malaria chemoprevention in Bama, Burkina Faso.
Somé FA, Bazié T, Ehrlich HY, Goodwin J, Lehane A, Neya C, Zachari K, Wade M, Ouattara JM, Foy BD, Dabiré RK, Parikh S, Ouédraogo JB. Somé FA, et al. Malar J. 2020 Jul 6;19(1):238. doi: 10.1186/s12936-020-03311-8. Malar J. 2020. PMID: 32631416 Free PMC article.
CYP2C8*2, associated with impaired amodiaquine metabolism, was common with an allelic frequency of 17.1% (95% CI 10.0-24.2). Day 7 concentration of DEAQ ranged from 0.48 to 362.80 ng/mL with a median concentration of 56.34 ng/mL. Pfmdr1 N86 predominated at both time …
CYP2C8*2, associated with impaired amodiaquine metabolism, was common with an allelic frequency of 17.1% (95% CI 10.0-24.2). Day 7 concentra …
Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.
Zongo I, Somé FA, Somda SA, Parikh S, Rouamba N, Rosenthal PJ, Tarning J, Lindegardh N, Nosten F, Ouédraogo JB. Zongo I, et al. PLoS One. 2014 Aug 18;9(8):e103200. doi: 10.1371/journal.pone.0103200. eCollection 2014. PLoS One. 2014. PMID: 25133389 Free PMC article. Clinical Trial.
However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. METHODS: We performed a single-arm open-label trial in Bobo-Dioulasso, Burkina Faso. A total of 379 partici …
However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, …
Neisseria gonorrhoeae and Chlamydia trachomatis infection in HIV-1-infected women taking antiretroviral therapy: a prospective cohort study from Burkina Faso.
Low AJ, Konate I, Nagot N, Weiss HA, Mabey D, Segondy M, Vickerman P, Meda N, van de Perre P, Mayaud P; Yerelon Cohort study group. Low AJ, et al. Sex Transm Infect. 2014 Mar;90(2):100-3. doi: 10.1136/sextrans-2013-051233. Epub 2013 Dec 13. Sex Transm Infect. 2014. PMID: 24337732 Free PMC article.
OBJECTIVES: Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) are common sexually transmitted infections (STI). ...Higher levels of education (aOR=0.17, 95% CI 0.03 to 0.92), and age greater than 35 years (aOR=0.07, 95% CI 0.01 to 0.92) were associated with lower o …
OBJECTIVES: Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) are common sexually transmitted infections (STI). ...Higher lev …
Prehospital use of magnesium sulfate as neuroprotection in acute stroke.
Saver JL, Starkman S, Eckstein M, Stratton SJ, Pratt FD, Hamilton S, Conwit R, Liebeskind DS, Sung G, Kramer I, Moreau G, Goldweber R, Sanossian N; FAST-MAG Investigators and Coordinators. Saver JL, et al. N Engl J Med. 2015 Feb 5;372(6):528-36. doi: 10.1056/NEJMoa1408827. N Engl J Med. 2015. PMID: 25651247 Free PMC article. Clinical Trial.
A Single-Dose Crossover Pharmacokinetic Comparison Study of Oral, Rectal and Topical Quetiapine in Healthy Adults.
Leung JG, Nelson S, Cunningham JL, Thompson VH, Bobo WV, Kung S, Dierkhising RA, Plevak MF, Lapid MI. Leung JG, et al. Clin Pharmacokinet. 2016 Aug;55(8):971-6. doi: 10.1007/s40262-016-0368-5. Clin Pharmacokinet. 2016. PMID: 26873228
RESULTS: Rectal quetiapine produced an area under the plasma concentration-time curve from time zero to infinity (AUC) approximately 90 % greater than that produced by an equal (milligram per milligram) dose of oral quetiapine (15,333 ng/mL versus 8118.8 ng/mL, p = …
RESULTS: Rectal quetiapine produced an area under the plasma concentration-time curve from time zero to infinity (AUC) approximately 90 % gr …
Design of a new multiplex PCR assay for rice pathogenic bacteria detection and its application to infer disease incidence and detect co-infection in rice fields in Burkina Faso.
Bangratz M, Wonni I, Kini K, Sondo M, Brugidou C, Béna G, Gnacko F, Barro M, Koebnik R, Silué D, Tollenaere C. Bangratz M, et al. PLoS One. 2020 Apr 27;15(4):e0232115. doi: 10.1371/journal.pone.0232115. eCollection 2020. PLoS One. 2020. PMID: 32339192 Free PMC article.
Moreover, sensitivity assessment for the detection of all five bacteria is reported to be at 0.5 ng DNA by mul. As a proof of concept, we applied the new molecular detection method to a set of 256 rice leaves collected from 16 fields in two irrigated areas in western Burki …
Moreover, sensitivity assessment for the detection of all five bacteria is reported to be at 0.5 ng DNA by mul. As a proof of concept …
Specific polycyclic aromatic hydrocarbons identified as ecological risk factors in the Lagos lagoon, Nigeria.
Sogbanmu TO, Osibona AO, Otitoloju AA. Sogbanmu TO, et al. Environ Pollut. 2019 Dec;255(Pt 2):113295. doi: 10.1016/j.envpol.2019.113295. Epub 2019 Sep 20. Environ Pollut. 2019. PMID: 31563786
The dominant fish species were Sarotherodon melanotheron (Black-Jawed Tilapia), Gerres melanopterus (Gerres), Liza falcipinnis (Sicklefin Mullet) and Pseudotolithus elongatus (Bobo Croaker) at Ilaje, Iddo, Atlas cove and Apapa zones respectively. ...
The dominant fish species were Sarotherodon melanotheron (Black-Jawed Tilapia), Gerres melanopterus (Gerres), Liza falcipinnis (Sicklefin Mu …
18 results