Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization.
Moon S, Kim W, Kim S, Kim Y, Song Y, Bilousov O, Kim J, Lee T, Cha B, Kim M, Kim H, Katanaev VL, Jho EH.
Moon S, et al.
EMBO Rep. 2017 Jan;18(1):61-71. doi: 10.15252/embr.201642683. Epub 2016 Dec 15.
EMBO Rep. 2017.
PMID: 27979972
Free PMC article.
We also find that with the increase in cell density, nuclear localization and the level of NLK are reduced, resulting in reduction in YAP phosphorylation at Ser128. Furthermore, knockdown of Nemo (the Drosophila NLK) in fruit fly wing imaginal discs results in reduced expr …
We also find that with the increase in cell density, nuclear localization and the level of NLK are reduced, resulting in reduction in YAP ph …