Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis.
Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Jäger H, Joost HG, Kulling S, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Vieths S, Wätjen W, Steinberg P.
Eisenbrand G, et al.
Arch Toxicol. 2022 Jun;96(6):1905-1914. doi: 10.1007/s00204-022-03296-0. Epub 2022 May 4.
Arch Toxicol. 2022.
PMID: 35504979
Therefore, putative combination effects in the oral cavity and the upper digestive tract may occur, but this has remained largely unexplored up to now. In this Guest Editorial, published evidence on exposure levels and biokinetics of nitrate/nitrite/NO(x), NOC and acetalde …
Therefore, putative combination effects in the oral cavity and the upper digestive tract may occur, but this has remained largely unexplored …
