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Year Number of Results
2004 1
2006 1
2007 2
2009 1
2010 1
2013 2
2014 2
2015 1
2016 1
2017 1
2018 2
2019 3
2020 1
2021 2
2022 2
2023 1
2024 1

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24 results

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Page 1
A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
Altwegg KA, Viswanadhapalli S, Mann M, Chakravarty D, Krishnan S, Liu Z, Liu J, Pratap UP, Ebrahimi B, Sanchez JR, Li X, Ma S, Park BH, Santhamma B, Chen Y, Lai Z, Raj GV, Yuan Y, Zhou D, Sareddy GR, Tekmal RR, McHardy S, Huang TH, Rao MK, Vankayalapati H, Vadlamudi RK. Altwegg KA, et al. Among authors: santhamma b. Cancer Res. 2022 Oct 17;82(20):3830-3844. doi: 10.1158/0008-5472.CAN-22-0698. Cancer Res. 2022. PMID: 35950923 Free PMC article.
The LIFR Inhibitor EC359 Effectively Targets Type II Endometrial Cancer by Blocking LIF/LIFR Oncogenic Signaling.
Spencer N, Rodriguez Sanchez AL, Gopalam R, Subbarayalu P, Medina DM, Yang X, Ramirez P, Randolph L, Aller EJ, Santhamma B, Rao MK, Tekmal RR, Nair HB, Kost ER, Vadlamudi RK, Viswanadhapalli S. Spencer N, et al. Among authors: santhamma b. Int J Mol Sci. 2023 Dec 13;24(24):17426. doi: 10.3390/ijms242417426. Int J Mol Sci. 2023. PMID: 38139260 Free PMC article.
Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth.
Blankenship L, Pratap UP, Yang X, Liu Z, Altwegg KA, Santhamma B, Ramasamy K, Konda S, Chen Y, Lai Z, Zheng S, Sareddy GR, Valente PT, Kost ER, Nair HB, Tekmal RR, Vadlamudi RK, Viswanadhapalli S. Blankenship L, et al. Among authors: santhamma b. Cancers (Basel). 2022 Nov 2;14(21):5400. doi: 10.3390/cancers14215400. Cancers (Basel). 2022. PMID: 36358818 Free PMC article.
LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer.
Li M, Viswanadhapalli S, Santhamma B, Pratap UP, Luo Y, Liu J, Altwegg KA, Tang W, Liu Z, Li X, Ebrahimi B, Yan H, Zou Y, Konda S, Sareddy GR, Xu Z, Chen Y, Rao MK, Brenner AJ, Kaklamani VG, Tekmal RR, Ahmed G, Raj GV, Nickisch KJ, Nair HB, Vadlamudi RK. Li M, et al. Among authors: santhamma b. Commun Biol. 2021 Oct 29;4(1):1235. doi: 10.1038/s42003-021-02741-7. Commun Biol. 2021. PMID: 34716410 Free PMC article.
EC330, a small-molecule compound, is a potential novel inhibitor of LIF signaling.
Yue X, Wu F, Wang J, Kim K, Santhamma B, Dileep KV, Zhang KYJ, Viswanadhapalli S, Vadlamudi RK, Ahmed G, Feng Z, Nickisch K, Hu W. Yue X, et al. Among authors: santhamma b. J Mol Cell Biol. 2020 Jul 3;12(6):477-480. doi: 10.1093/jmcb/mjaa008. J Mol Cell Biol. 2020. PMID: 32221559 Free PMC article. No abstract available.
LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer.
Tang W, Ramasamy K, Pillai SMA, Santhamma B, Konda S, Pitta Venkata P, Blankenship L, Liu J, Liu Z, Altwegg KA, Ebrahimi B, Pratap UP, Li X, Valente PT, Kost E, Sareddy GR, Vadlamudi RK, Nair HB, Tekmal RR, Viswanadhapalli S. Tang W, et al. Among authors: santhamma b. Cell Death Discov. 2021 Aug 16;7(1):216. doi: 10.1038/s41420-021-00603-z. Cell Death Discov. 2021. PMID: 34400617 Free PMC article.
Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling.
Singhal H, Greene ME, Zarnke AL, Laine M, Al Abosy R, Chang YF, Dembo AG, Schoenfelt K, Vadhi R, Qiu X, Rao P, Santhamma B, Nair HB, Nickisch KJ, Long HW, Becker L, Brown M, Greene GL. Singhal H, et al. Among authors: santhamma b. Oncotarget. 2017 Sep 28;9(4):4282-4300. doi: 10.18632/oncotarget.21378. eCollection 2018 Jan 12. Oncotarget. 2017. PMID: 29435103 Free PMC article.
N-heterocyclic carbenes: reagents, not just ligands!
Nair V, Bindu S, Sreekumar V. Nair V, et al. Among authors: bindu s. Angew Chem Int Ed Engl. 2004 Oct 4;43(39):5130-5. doi: 10.1002/anie.200301714. Angew Chem Int Ed Engl. 2004. PMID: 15372548
24 results