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Showing results for binding lian
Your search for Binbin Lian retrieved no results
System analysis of Huang-Lian-Jie-Du-Tang and their key active ingredients for overcoming CML resistance by suppression of leukemia stem cells.
Huang G, Yin Z, Wang X, Wen Z, Su R, Li C, Liu Y, Yang J, Hu H, Nie H, Zeng X, Fei J. Huang G, et al. Phytomedicine. 2023 Aug;117:154918. doi: 10.1016/j.phymed.2023.154918. Epub 2023 Jun 9. Phytomedicine. 2023. PMID: 37329755
PURPOSE: To study the key active ingredients and corresponding target proteins in Huang-Lian-Jie-Du-Tang (HLJDT) against BCR-ABL1-independent CML resistance to therapeutics, and then explore its mechanism of against CML drug resistance. ...Monitoring therapeutic effect on …
PURPOSE: To study the key active ingredients and corresponding target proteins in Huang-Lian-Jie-Du-Tang (HLJDT) against BCR-ABL1-ind …
The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors.
Lian H, Zang R, Wei J, Ye W, Hu MM, Chen YD, Zhang XN, Guo Y, Lei CQ, Yang Q, Luo WW, Li S, Shu HB. Lian H, et al. Immunity. 2018 Sep 18;49(3):438-448.e5. doi: 10.1016/j.immuni.2018.08.014. Epub 2018 Sep 4. Immunity. 2018. PMID: 30193849 Free article.
Recognition of viral RNA by the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) initiates innate antiviral immune response. How the binding of viral RNA to and activation of the RLRs are regulated remains enigmatic. ...ZCCHC3 was associated with RIG-I and MDA5 …
Recognition of viral RNA by the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) initiates innate antiviral immune response. How …
Deciphering the Epitranscriptome in Cancer.
Lian H, Wang QH, Zhu CB, Ma J, Jin WL. Lian H, et al. Trends Cancer. 2018 Mar;4(3):207-221. doi: 10.1016/j.trecan.2018.01.006. Epub 2018 Feb 21. Trends Cancer. 2018. PMID: 29506671 Review.
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.
Tian H, Liu C, Yu J, Han J, Du J, Liang S, Wang W, Liu Q, Lian R, Zhu T, Wu S, Tao T, Ye Y, Zhao J, Yang Y, Zhu X, Cai J, Wu J, Li M. Tian H, et al. Cell Discov. 2023 Apr 18;9(1):41. doi: 10.1038/s41421-023-00528-0. Cell Discov. 2023. PMID: 37072414 Free PMC article.
Here, we found that SMAD7, a direct downstream transcriptional target and also a key antagonist of TGF-beta signaling, is transcriptionally suppressed in lung adenocarcinoma (LAD) due to DNA hypermethylation. We further identified that PHF14 binds DNMT3B and serves as a DN …
Here, we found that SMAD7, a direct downstream transcriptional target and also a key antagonist of TGF-beta signaling, is transcriptionally …
Heparin-Binding Epidermal Growth Factor-Like Growth Factor as a Potent Target for Breast Cancer Therapy.
Lian C, Ruan L, Shang D, Wu Y, Lu Y, Lü P, Yang Y, Wei Y, Dong X, Ren D, Chen K, Liu H, Tu Z. Lian C, et al. Cancer Biother Radiopharm. 2016 Apr;31(3):85-90. doi: 10.1089/cbr.2015.1956. Cancer Biother Radiopharm. 2016. PMID: 27093342 Review.
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) belongs to the EGF family and exhibits its activity after binding to its receptors in autocrine, paracrine, and juxtacrine interactions. ...
Heparin-binding epidermal growth factor-like growth factor (HB-EGF) belongs to the EGF family and exhibits its activity after bind …
Carboxylated calcium-binding proteins and vitamin K.
Gallop PM, Lian JB, Hauschka PV. Gallop PM, et al. N Engl J Med. 1980 Jun 26;302(26):1460-6. doi: 10.1056/NEJM198006263022608. N Engl J Med. 1980. PMID: 6990261 Review. No abstract available.
Molecular mechanism of the wake-promoting agent TAK-925.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Nat Commun. 2022 May 25;13(1):2902. doi: 10.1038/s41467-022-30601-3. Nat Commun. 2022. PMID: 35614071 Free PMC article.
Finally, differences in the polarity of interactions at the G protein binding interfaces help to rationalize OX(2)R's coupling selectivity for G(q) signaling. The mechanisms of TAK-925's binding, activation, and selectivity presented herein will aid in understanding …
Finally, differences in the polarity of interactions at the G protein binding interfaces help to rationalize OX(2)R's coupling select …
Diagnostic accuracy of mac-2-binding protein glycosylation isomer for diagnosing hepatitis B-related fibrosis: A meta-analysis.
Lian MJ, Chen ZQ, Wang QM, Zheng GS, Hong GL. Lian MJ, et al. J Dig Dis. 2022 Oct;23(10):550-560. doi: 10.1111/1751-2980.13140. Epub 2022 Dec 13. J Dig Dis. 2022. PMID: 36251470 Review.
OBJECTIVES: Mac-2-binding protein glycosylation isomer (M2BPGi) is a novel biomarker for liver fibrosis. ...
OBJECTIVES: Mac-2-binding protein glycosylation isomer (M2BPGi) is a novel biomarker for liver fibrosis. ...
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma.
Wang J, Zhang X, Ma X, Chen D, Cai M, Xiao L, Li J, Huang Z, Huang Y, Lian Y. Wang J, et al. J Exp Clin Cancer Res. 2023 Nov 16;42(1):303. doi: 10.1186/s13046-023-02885-w. J Exp Clin Cancer Res. 2023. PMID: 37968706 Free PMC article.
Our previous study has demonstrated the critical role of CacyBP/SIP (Calcyclin-Binding Protein and Siah-1 Interacting Protein) as a regulator of HCC development and progression. ...RESULTS: We identified that CacyBP was positively correlated with Myd88, a master regulator …
Our previous study has demonstrated the critical role of CacyBP/SIP (Calcyclin-Binding Protein and Siah-1 Interacting Protein) as a r …
Mechanisms of pancreatic tumor suppression mediated by Xiang-lian pill: An integrated in silico exploration and experimental validation.
Jiao J, Cheng CS, Xu P, Yang P, Zhang K, Jing Y, Chen Z. Jiao J, et al. J Ethnopharmacol. 2022 Nov 15;298:115586. doi: 10.1016/j.jep.2022.115586. Epub 2022 Aug 2. J Ethnopharmacol. 2022. PMID: 35931303 Free article.
Molecular docking and the cellular thermal shift assay were performed to test the binding efficiency between ingredients and targets. A murine pancreatic cancer model was established and administered different doses of the Xiang-lian pill. ...The main active ingredi …
Molecular docking and the cellular thermal shift assay were performed to test the binding efficiency between ingredients and targets. …
1,663 results