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Page 1
Showing results for binding hao
Search for Binbin Hao instead (2 results)
BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis.
Huang C, Li H, Xu Y, Xu C, Sun H, Li Z, Ge Y, Wang H, Zhao T, Gao S, Wang X, Yang S, Sun P, Liu Z, Liu J, Chang A, Hao J. Huang C, et al. Signal Transduct Target Ther. 2023 Jul 14;8(1):271. doi: 10.1038/s41392-023-01478-5. Signal Transduct Target Ther. 2023. PMID: 37443111 Free PMC article.
In cells and mice with xenograft tumors, BICC1 facilitated angiogenesis in pancreatic cancer in a VEGF-independent manner. Mechanistically, as an RNA binding protein, BICC1 bounds to the 3'UTR of Lipocalin-2 (LCN2) mRNA and post-transcriptionally up-regulated LCN2 expressi …
In cells and mice with xenograft tumors, BICC1 facilitated angiogenesis in pancreatic cancer in a VEGF-independent manner. Mechanistically, …
Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin.
Rubinstein MR, Wang X, Liu W, Hao Y, Cai G, Han YW. Rubinstein MR, et al. Cell Host Microbe. 2013 Aug 14;14(2):195-206. doi: 10.1016/j.chom.2013.07.012. Cell Host Microbe. 2013. PMID: 23954158 Free PMC article.
We demonstrate that Fn adheres to, invades, and induces oncogenic and inflammatory responses to stimulate growth of CRC cells through its unique FadA adhesin. FadA binds to E-cadherin, activates beta-catenin signaling, and differentially regulates the inflammatory and onco …
We demonstrate that Fn adheres to, invades, and induces oncogenic and inflammatory responses to stimulate growth of CRC cells through its un …
Retraction.
[No authors listed] [No authors listed] J Cell Physiol. 2022 Mar;237(3):2006. doi: 10.1002/jcp.30518. Epub 2021 Jul 20. J Cell Physiol. 2022. PMID: 34287869
Retraction: "Effects of microRNA-370 on mesangial cell proliferation and extracellular matrix accumulation by binding to canopy 1 in a rat model of diabetic nephropathy," by Feng-Na Yu, Ming-Lan Hu, Xin-Fang Wang, Xiang-Ping Li, Bei-Hao Zhang, Xiao-Qing Lu, Rui-Qian …
Retraction: "Effects of microRNA-370 on mesangial cell proliferation and extracellular matrix accumulation by binding to canopy 1 in …
Identification of SIRT3 as an eraser of H4K16la.
Fan Z, Liu Z, Zhang N, Wei W, Cheng K, Sun H, Hao Q. Fan Z, et al. iScience. 2023 Aug 28;26(10):107757. doi: 10.1016/j.isci.2023.107757. eCollection 2023 Oct 20. iScience. 2023. PMID: 37720100 Free PMC article.
In this study, we observed that SIRT3 exhibits a higher eraser activity against the H4K16la site than the other human Sirtuins. Crystal structures revealed the detailed binding mechanisms between lactyl-lysine peptides and SIRT3. Furthermore, a chemical probe, p-H4K16laAlk …
In this study, we observed that SIRT3 exhibits a higher eraser activity against the H4K16la site than the other human Sirtuins. Crystal stru …
Role of the RNA-binding protein family in gynecologic cancers.
Hao L, Zhang J, Liu Z, Zhang Z, Mao T, Guo J. Hao L, et al. Am J Cancer Res. 2023 Aug 15;13(8):3799-3821. eCollection 2023. Am J Cancer Res. 2023. PMID: 37693158 Free PMC article. Review.
Although early-stage gynecological cancers show good outcomes after standardized treatment, the prognosis of patients with advanced, met-astatic, and recurrent cancers is poor. RNA-binding proteins (RBPs) are important cellular proteins that interact with RNA through RNA- …
Although early-stage gynecological cancers show good outcomes after standardized treatment, the prognosis of patients with advanced, met-ast …
Fragment-based drug discovery supports drugging 'undruggable' protein-protein interactions.
Wang ZZ, Shi XX, Huang GY, Hao GF, Yang GF. Wang ZZ, et al. Trends Biochem Sci. 2023 Jun;48(6):539-552. doi: 10.1016/j.tibs.2023.01.008. Epub 2023 Feb 24. Trends Biochem Sci. 2023. PMID: 36841635 Review.
Targeting hot spots that have essential roles in both fragment binding and PPIs provides a shortcut for the development of PPI modulators via FBDD. ...
Targeting hot spots that have essential roles in both fragment binding and PPIs provides a shortcut for the development of PPI modula …
Unraveling linker histone interactions in nucleosomes.
Hao F, Kale S, Dimitrov S, Hayes JJ. Hao F, et al. Curr Opin Struct Biol. 2021 Dec;71:87-93. doi: 10.1016/j.sbi.2021.06.001. Epub 2021 Jul 8. Curr Opin Struct Biol. 2021. PMID: 34246862 Free PMC article. Review.
Although these studies have led to a detailed understanding of the interactions and dynamics of H1 globular domains in the canonical on-dyad nucleosome binding pocket, more information regarding the intrinsically disordered N-terminal and C-terminal domains is needed. ...
Although these studies have led to a detailed understanding of the interactions and dynamics of H1 globular domains in the canonical on-dyad …
Negatively cooperative binding properties of human cytochrome P450 2E1 with monocyclic substrates.
Ping J, Wang YJ, Wang JF, Li X, Li YX, Hao P. Ping J, et al. Curr Drug Metab. 2012 Sep 1;13(7):1024-31. doi: 10.2174/138920012802138606. Curr Drug Metab. 2012. PMID: 22591346 Review.
Further studies show that the non-hyperbolic kinetic behaviors are associated with multiple substrate binding, which is also known as the cooperative binding properties. However, the detailed mechanism for the cooperative binding is not clear by now. In this …
Further studies show that the non-hyperbolic kinetic behaviors are associated with multiple substrate binding, which is also known as …
Rho-dependent transcription termination: a revisionist view.
Hao Z, Svetlov V, Nudler E. Hao Z, et al. Transcription. 2021 Aug;12(4):171-181. doi: 10.1080/21541264.2021.1991773. Epub 2021 Oct 27. Transcription. 2021. PMID: 34705601 Free PMC article. Review.
The broadly accepted ("textbook") model posits a series of steps, wherein Rho first binds C-rich Rho utilization (rut) sites on nascent RNA, uses its ATP-dependent translocase activity to catch up with RNA polymerase (RNAP), and either pulls the transcript from the elongat …
The broadly accepted ("textbook") model posits a series of steps, wherein Rho first binds C-rich Rho utilization (rut) sites on nasce …
4,324 results