Eosinophilic myocarditis due to Churg-Strauss syndrome mimicking reversible dilated cardiomyopathy

Heart Lung. 2014 Jan-Feb;43(1):45-7. doi: 10.1016/j.hrtlng.2013.09.006. Epub 2013 Oct 2.

Abstract

A 41-year-old woman with a history of asthma arrived at the emergency room of our hospital with dyspnea. The electrocardiogram showed no specific results. Echocardiography defects revealed an obvious decrease in the left ventricular systolic function and enlargement of the left chamber. We initially considered her condition to be dilated cardiomyopathy. However, she had eosinophilia in the peripheral blood and elevated cardiac enzymes. The coronary angiography showed normal coronary arteries. Single photon emission computed tomography (SPECT) showed infiltrative myocardial disease. She was then diagnosed with eosinophil infiltrations. Combined with peripheral nerve injury and lung involvement, she was diagnosed as having Churg-Strauss syndrome. After initiating prednisone treatment, her eosinophilia and rising cardiac enzymes recovered to normal, and both her echocardiographic abnormalities and symptoms noticeably improved.

Keywords: Churg–Strauss syndrome; Dilated cardiomyopathy; Eosinophilic myocarditis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Asthma / complications
  • Cardiomyopathy, Dilated / diagnosis*
  • Churg-Strauss Syndrome / complications
  • Churg-Strauss Syndrome / diagnosis*
  • Diagnosis, Differential
  • Echocardiography
  • Eosinophilia / diagnosis*
  • Eosinophilia / etiology
  • Female
  • Humans
  • Myocarditis / diagnosis*
  • Myocarditis / etiology
  • Tomography, Emission-Computed, Single-Photon