Solvent free, microwave assisted conversion of aldehydes into nitriles and oximes in the presence of NH2OH x HCl and TiO2

Lucas Villas-Boas Hoelz; Biank Tomaz Gonçalves; José Celestino Barros; Joaquim Fernando Mendes da Silva

doi:10.3390/molecules15010094

Solvent free, microwave assisted conversion of aldehydes into nitriles and oximes in the presence of NH2OH x HCl and TiO2

Molecules. 2009 Dec 29;15(1):94-9. doi: 10.3390/molecules15010094.

Authors

Lucas Villas-Boas Hoelz¹, Biank Tomaz Gonçalves, José Celestino Barros, Joaquim Fernando Mendes da Silva

Affiliation

¹ Departamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 149, CT Bloco A, Cidade Universitária, Rio de Janeiro, RJ 21941-909, RJ, Brazil.

Abstract

Aromatic aldehydes bearing electron-donating groups are easily converted into their respective nitriles using NH(2)OH.HCl and TiO(2) under microwave irradiation, while those bearing an electron-withdrawing group give the corresponding oximes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry*
Ammonium Hydroxide
Benzaldehydes / chemistry
Chromatography, Gas
Hydrochloric Acid / chemistry*
Hydroxides / chemistry*
Mass Spectrometry
Microwaves*
Nitriles / chemistry*
Oximes / chemistry*
Solvents / chemistry
Time Factors
Titanium / chemistry*

Substances

Aldehydes
Benzaldehydes
Hydroxides
Nitriles
Oximes
Solvents
titanium dioxide
Ammonium Hydroxide
vanillin
Titanium
Hydrochloric Acid