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Page 1
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
Sarkar S, Nguyen HM, Malovic E, Luo J, Langley M, Palanisamy BN, Singh N, Manne S, Neal M, Gabrielle M, Abdalla A, Anantharam P, Rokad D, Panicker N, Singh V, Ay M, Charli A, Harischandra D, Jin LW, Jin H, Rangaraju S, Anantharam V, Wulff H, Kanthasamy AG. Sarkar S, et al. Among authors: palanisamy bn. J Clin Invest. 2020 Aug 3;130(8):4195-4212. doi: 10.1172/JCI136174. J Clin Invest. 2020. PMID: 32597830 Free PMC article.
Environmental neurotoxic pesticide exposure induces gut inflammation and enteric neuronal degeneration by impairing enteric glial mitochondrial function in pesticide models of Parkinson's disease: Potential relevance to gut-brain axis inflammation in Parkinson's disease pathogenesis.
Palanisamy BN, Sarkar S, Malovic E, Samidurai M, Charli A, Zenitsky G, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Palanisamy BN, et al. Int J Biochem Cell Biol. 2022 Jun;147:106225. doi: 10.1016/j.biocel.2022.106225. Epub 2022 May 12. Int J Biochem Cell Biol. 2022. PMID: 35550926 Free PMC article.
MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson's disease.
Ghaisas S, Langley MR, Palanisamy BN, Dutta S, Narayanaswamy K, Plummer PJ, Sarkar S, Ay M, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Ghaisas S, et al. Among authors: palanisamy bn. Neurotoxicology. 2019 Dec;75:186-199. doi: 10.1016/j.neuro.2019.09.004. Epub 2019 Sep 7. Neurotoxicology. 2019. PMID: 31505196 Free PMC article.
PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway.
Samidurai M, Palanisamy BN, Bargues-Carot A, Hepker M, Kondru N, Manne S, Zenitsky G, Jin H, Anantharam V, Kanthasamy AG, Kanthasamy A. Samidurai M, et al. Among authors: palanisamy bn. Front Aging Neurosci. 2021 Jul 2;13:661505. doi: 10.3389/fnagi.2021.661505. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34276337 Free PMC article.
Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.
Langley MR, Ghaisas S, Ay M, Luo J, Palanisamy BN, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Langley MR, et al. Among authors: palanisamy bn. Neurotoxicology. 2018 Jan;64:240-255. doi: 10.1016/j.neuro.2017.06.002. Epub 2017 Jun 20. Neurotoxicology. 2018. PMID: 28595911 Free PMC article.
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease.
Sarkar S, Malovic E, Harishchandra DS, Ghaisas S, Panicker N, Charli A, Palanisamy BN, Rokad D, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Sarkar S, et al. Among authors: palanisamy bn. NPJ Parkinsons Dis. 2017 Oct 17;3:30. doi: 10.1038/s41531-017-0032-2. eCollection 2017. NPJ Parkinsons Dis. 2017. PMID: 29057315 Free PMC article.