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Is 1,8-Cineole-Rich Extract of Small Cardamom Seeds More Effective in Preventing Alzheimer's Disease than 1,8-Cineole Alone?
Paul K, Ganguly U, Chakrabarti S, Bhattacharjee P. Paul K, et al. Neuromolecular Med. 2020 Mar;22(1):150-158. doi: 10.1007/s12017-019-08574-2. Epub 2019 Oct 18. Neuromolecular Med. 2020. PMID: 31628580
The present study demonstrates the efficacies of synthetic 1,8-cineole and an 1,8-cineole-rich supercritical carbon dioxide (SC-CO(2)) extract of small cardamom seeds in preventing oligomerization of amyloid beta peptide (Abeta42) and inhibiting iron-dependent oxyradical p …
The present study demonstrates the efficacies of synthetic 1,8-cineole and an 1,8-cineole-rich supercritical carbon dioxide (SC-CO(2)) extra …
A cytosolic bifunctional geranyl/farnesyl diphosphate synthase provides MVA-derived GPP for geraniol biosynthesis in rose flowers.
Conart C, Bomzan DP, Huang XQ, Bassard JE, Paramita SN, Saint-Marcoux D, Rius-Bony A, Hivert G, Anchisi A, Schaller H, Hamama L, Magnard JL, Lipko A, Swiezewska E, Jame P, Riveill G, Hibrand-Saint Oyant L, Rohmer M, Lewinsohn E, Dudareva N, Baudino S, Caissard JC, Boachon B. Conart C, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2221440120. doi: 10.1073/pnas.2221440120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126706 Free PMC article.
The downregulation and overexpression of RcG/FPPS1 in rose petals affected not only geraniol and germacrene D emissions but also dihydro-beta-ionol, the latter due to metabolic cross talk of RcG/FPPS1-dependent isoprenoid intermediates trafficking from the cytosol to plast …
The downregulation and overexpression of RcG/FPPS1 in rose petals affected not only geraniol and germacrene D emissions but also dihydro- …
Curcumin for the Prevention of Epithelial-Mesenchymal Transition in Endoxifen-Treated MCF-7 Breast Cancer Cel.
Paramita P, Wardhani BW, Wanandi SI, Louisa M. Paramita P, et al. Asian Pac J Cancer Prev. 2018 May 26;19(5):1243-1249. doi: 10.22034/APJCP.2018.19.5.1243. Asian Pac J Cancer Prev. 2018. PMID: 29801408 Free PMC article.
Result: MCF-7 cell viability was increased in endoxifen + beta-estradiol group. Cell viability was significantly decreased in curcumin 17 muM, but not in curcumin 8.5 muM group. Analysis of EMT markers at week 8 indicates that there were increase in vimentin and TGF-bet …
Result: MCF-7 cell viability was increased in endoxifen + beta-estradiol group. Cell viability was significantly decreased in curcumi …
Exploring the potential of T7 bacteriophage protein Gp2 as a novel inhibitor of mycobacterial RNA polymerase.
du Plessis J, Cloete R, Burchell L, Sarkar P, Warren RM, Christoffels A, Wigneshweraraj S, Sampson SL. du Plessis J, et al. Tuberculosis (Edinb). 2017 Sep;106:82-90. doi: 10.1016/j.tube.2017.07.004. Epub 2017 Jul 18. Tuberculosis (Edinb). 2017. PMID: 28802409
Phages inhibit bacterial gene transcription through phage-encoded proteins which bind to RNA polymerase (RNAP), thereby preventing bacterial transcription. Gp2, a T7 phage protein which binds to the beta prime (beta') subunit of RNAP in Escherichia coli, has been we …
Phages inhibit bacterial gene transcription through phage-encoded proteins which bind to RNA polymerase (RNAP), thereby preventing bacterial …