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Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Oh DH, Ma X, Hogg SJ, He J, Kearney C, Brasacchio D, Susanto O, Maher B, Jennings IG, Newbold A, Fraser P, Gruber E, Kats LM, Gregory GP, Johnstone RW, Thompson PE, Shortt J. Oh DH, et al. Among authors: maher b. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2306414120. doi: 10.1073/pnas.2306414120. Epub 2023 Aug 29. Proc Natl Acad Sci U S A. 2023. PMID: 37643213 Free PMC article.
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma.
Wong J, Gruber E, Maher B, Waltham M, Sabouri-Thompson Z, Jong I, Luong Q, Levy S, Kumar B, Brasacchio D, Jia W, So J, Skinner H, Lewis A, Hogg SJ, Vervoort S, DiCorleto C, Uhe M, Gamgee J, Opat S, Gregory GP, Polekhina G, Reynolds J, Hawkes EA, Kailainathan G, Gasiorowski R, Kats LM, Shortt J. Wong J, et al. Among authors: maher b. Leukemia. 2022 Jun;36(6):1654-1665. doi: 10.1038/s41375-022-01571-8. Epub 2022 Apr 22. Leukemia. 2022. PMID: 35459873 Free PMC article. Clinical Trial.