CDK6 inhibits white to beige fat transition by suppressing RUNX1.
Hou X, Zhang Y, Li W, Hu AJ, Luo C, Zhou W, Hu JK, Daniele SG, Wang J, Sheng J, Fan Y, Greenberg AS, Farmer SR, Hu MG.
Hou X, et al.
Nat Commun. 2018 Mar 9;9(1):1023. doi: 10.1038/s41467-018-03451-1.
Nat Commun. 2018.
PMID: 29523786
Free PMC article.
Whereas white adipose tissue depots contribute to the development of metabolic diseases, brown and beige adipose tissue has beneficial metabolic effects. Here we show that CDK6 regulates beige adipocyte formation. We demonstrate that mice lacking the CDK6 protein or …
Whereas white adipose tissue depots contribute to the development of metabolic diseases, brown and beige adipose tissue has beneficia …