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Editorial: CNS tumor metabolism: targets, markers, and challenges.
Fernandez-Gil BI, Larion M. Fernandez-Gil BI, et al. Front Cell Neurosci. 2024 Mar 27;18:1401687. doi: 10.3389/fncel.2024.1401687. eCollection 2024. Front Cell Neurosci. 2024. PMID: 38601024 Free PMC article. No abstract available.
Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Martinez-Ruiz L, Florido J, Rodriguez-Santana C, López-Rodríguez A, Guerra-Librero A, Fernández-Gil BI, García-Tárraga P, Garcia-Verdugo JM, Oppel F, Sudhoff H, Sánchez-Porras D, Ten-Steve A, Fernández-Martínez J, González-García P, Rusanova I, Acuña-Castroviejo D, Carriel V, Escames G. Martinez-Ruiz L, et al. Among authors: fernandez gil bi. Biomed Pharmacother. 2023 Nov;167:115518. doi: 10.1016/j.biopha.2023.115518. Epub 2023 Sep 15. Biomed Pharmacother. 2023. PMID: 37717534 Free article.
Melatonin Treatment Triggers Metabolic and Intracellular pH Imbalance in Glioblastoma.
Fernandez-Gil BI, Otamendi-Lopez A, Bechtle A, Vazquez-Ramos CA, Qosja N, Suarez-Meade P, Sarabia-Estrada R, Jentoft ME, Guerrero-Cázares H, Escames G, Schiapparelli P, Quiñones-Hinojosa A. Fernandez-Gil BI, et al. Cells. 2022 Nov 2;11(21):3467. doi: 10.3390/cells11213467. Cells. 2022. PMID: 36359862 Free PMC article.
Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway.
Saeui CT, Shah SR, Fernandez-Gil BI, Zhang C, Agatemor C, Dammen-Brower K, Mathew MP, Buettner M, Gowda P, Khare P, Otamendi-Lopez A, Yang S, Zhang H, Le A, Quinoñes-Hinojosa A, Yarema KJ. Saeui CT, et al. Among authors: fernandez gil bi. ACS Chem Biol. 2023 Jan 20;18(1):151-165. doi: 10.1021/acschembio.2c00784. Epub 2023 Jan 10. ACS Chem Biol. 2023. PMID: 36626752
Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function.
Guerra-Librero A, Fernandez-Gil BI, Florido J, Martinez-Ruiz L, Rodríguez-Santana C, Shen YQ, García-Verdugo JM, López-Rodríguez A, Rusanova I, Quiñones-Hinojosa A, Acuña-Castroviejo D, Marruecos J, De Haro T, Escames G. Guerra-Librero A, et al. Among authors: fernandez gil bi. Antioxidants (Basel). 2021 Apr 14;10(4):603. doi: 10.3390/antiox10040603. Antioxidants (Basel). 2021. PMID: 33919790 Free PMC article.
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RKA, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D. Díaz-Casado ME, et al. Among authors: fernandez gil bi. Zebrafish. 2018 Feb;15(1):15-26. doi: 10.1089/zeb.2017.1479. Epub 2017 Nov 29. Zebrafish. 2018. PMID: 29185873
Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.
Mendivil-Perez M, Soto-Mercado V, Guerra-Librero A, Fernandez-Gil BI, Florido J, Shen YQ, Tejada MA, Capilla-Gonzalez V, Rusanova I, Garcia-Verdugo JM, Acuña-Castroviejo D, López LC, Velez-Pardo C, Jimenez-Del-Rio M, Ferrer JM, Escames G. Mendivil-Perez M, et al. Among authors: fernandez gil bi. J Pineal Res. 2017 Sep;63(2). doi: 10.1111/jpi.12415. Epub 2017 May 18. J Pineal Res. 2017. PMID: 28423196
Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy.
Fernandez-Gil BI, Guerra-Librero A, Shen YQ, Florido J, Martínez-Ruiz L, García-López S, Adan C, Rodríguez-Santana C, Acuña-Castroviejo D, Quiñones-Hinojosa A, Fernández-Martínez J, Abdel Moneim AE, López LC, Rodríguez Ferrer JM, Escames G. Fernandez-Gil BI, et al. Oxid Med Cell Longev. 2019 Feb 28;2019:7187128. doi: 10.1155/2019/7187128. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 30944696 Free PMC article.
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G. Shen YQ, et al. Among authors: fernandez gil bi. J Pineal Res. 2018 Apr;64(3). doi: 10.1111/jpi.12461. Epub 2018 Jan 9. J Pineal Res. 2018. PMID: 29247557