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Targeting Serotonin 2A and Adrenergic α1 Receptors for Ocular Antihypertensive Agents: Discovery of 3,4-Dihydropyrazino[1,2-b]indazol-1(2H)-one Derivatives.
Furlotti G, Alisi MA, Cazzolla N, Ceccacci F, Garrone B, Gasperi T, La Bella A, Leonelli F, Loreto MA, Magarò G, Mangano G, Bettolo RM, Masini E, Miceli M, Migneco LM, Vitiello M. Furlotti G, et al. Among authors: garrone b. ChemMedChem. 2018 Aug 10;13(15):1597-1607. doi: 10.1002/cmdc.201800199. Epub 2018 Jul 9. ChemMedChem. 2018. PMID: 29873449
Pharmacological Characterization of the Microsomal Prostaglandin E2 Synthase-1 Inhibitor AF3485 In Vitro and In Vivo.
Di Francesco L, Bruno A, Ricciotti E, Tacconelli S, Dovizio M, Guillem-Llobat P, Alisi MA, Garrone B, Coletta I, Mangano G, Milanese C, FitzGerald GA, Patrignani P. Di Francesco L, et al. Among authors: garrone b. Front Pharmacol. 2020 Apr 2;11:374. doi: 10.3389/fphar.2020.00374. eCollection 2020. Front Pharmacol. 2020. PMID: 32317963 Free PMC article.
Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue and In Vivo Activity in a Mood Disorder Model.
Prati F, Buonfiglio R, Furlotti G, Cavarischia C, Mangano G, Picollo R, Oggianu L, di Matteo A, Olivieri S, Bovi G, Porceddu PF, Reggiani A, Garrone B, Di Giorgio FP, Ombrato R. Prati F, et al. Among authors: garrone b. ACS Med Chem Lett. 2020 Mar 24;11(5):825-831. doi: 10.1021/acsmedchemlett.9b00633. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435391 Free PMC article.
5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis.
Olivero G, Grilli M, Vergassola M, Bonfiglio T, Padolecchia C, Garrone B, Di Giorgio FP, Tongiani S, Usai C, Marchi M, Pittaluga A. Olivero G, et al. Among authors: garrone b. Neuropharmacology. 2018 May 1;133:429-439. doi: 10.1016/j.neuropharm.2018.02.030. Epub 2018 Feb 27. Neuropharmacology. 2018. PMID: 29499271
Discovery and pharmacological profile of new 1H-indazole-3-carboxamide and 2H-pyrrolo[3,4-c]quinoline derivatives as selective serotonin 4 receptor ligands.
Furlotti G, Alisi MA, Apicella C, Capezzone de Joannon A, Cazzolla N, Costi R, Cuzzucoli Crucitti G, Garrone B, Iacovo A, Magarò G, Mangano G, Miele G, Ombrato R, Pescatori L, Polenzani L, Rosi F, Vitiello M, Di Santo R. Furlotti G, et al. Among authors: garrone b. J Med Chem. 2012 Nov 26;55(22):9446-66. doi: 10.1021/jm300573d. Epub 2012 Oct 24. J Med Chem. 2012. PMID: 23043420
16 results