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2012 | 2 |
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Page 1
Novel Selective Butyrylcholinesterase Inhibitors Incorporating Antioxidant Functionalities as Potential Bimodal Therapeutics for Alzheimer's Disease.
Molecules. 2016 Apr 1;21(4):440. doi: 10.3390/molecules21040440.
Molecules. 2016.
PMID: 27534722
Free PMC article.
Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.
Sawatzky E, Wehle S, Kling B, Wendrich J, Bringmann G, Sotriffer CA, Heilmann J, Decker M.
Sawatzky E, et al. Among authors: kling b.
J Med Chem. 2016 Mar 10;59(5):2067-82. doi: 10.1021/acs.jmedchem.5b01674. Epub 2016 Feb 17.
J Med Chem. 2016.
PMID: 26886849
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Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine.
Huang G, Kling B, Darras FH, Heilmann J, Decker M.
Huang G, et al. Among authors: kling b.
Eur J Med Chem. 2014 Jun 23;81:15-21. doi: 10.1016/j.ejmech.2014.05.002. Epub 2014 May 4.
Eur J Med Chem. 2014.
PMID: 24819955
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Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer.
Darras FH, Kling B, Heilmann J, Decker M.
Darras FH, et al. Among authors: kling b.
ACS Med Chem Lett. 2012 Aug 22;3(11):914-9. doi: 10.1021/ml3001825. eCollection 2012 Nov 8.
ACS Med Chem Lett. 2012.
PMID: 24900407
Free PMC article.
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Tacrine-silibinin codrug shows neuro- and hepatoprotective effects in vitro and pro-cognitive and hepatoprotective effects in vivo.
Chen X, Zenger K, Lupp A, Kling B, Heilmann J, Fleck C, Kraus B, Decker M.
Chen X, et al. Among authors: kling b.
J Med Chem. 2012 Jun 14;55(11):5231-42. doi: 10.1021/jm300246n. Epub 2012 May 24.
J Med Chem. 2012.
PMID: 22624880
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Cyclic acyl guanidines bearing carbamate moieties allow potent and dirigible cholinesterase inhibition of either acetyl- or butyrylcholinesterase.
Darras FH, Kling B, Sawatzky E, Heilmann J, Decker M.
Darras FH, et al. Among authors: kling b.
Bioorg Med Chem. 2014 Sep 1;22(17):5020-34. doi: 10.1016/j.bmc.2014.06.010. Epub 2014 Jun 26.
Bioorg Med Chem. 2014.
PMID: 25059502
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Flavonoids, flavonoid metabolites, and phenolic acids inhibit oxidative stress in the neuronal cell line HT-22 monitored by ECIS and MTT assay: a comparative study.
Kling B, Bücherl D, Palatzky P, Matysik FM, Decker M, Wegener J, Heilmann J.
Kling B, et al.
J Nat Prod. 2014 Mar 28;77(3):446-54. doi: 10.1021/np400518k. Epub 2013 Nov 18.
J Nat Prod. 2014.
PMID: 24245939
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