Prediagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma.
Stepien M, Lopez-Nogueroles M, Lahoz A, Kühn T, Perlemuter G, Voican C, Ciocan D, Boutron-Ruault MC, Jansen E, Viallon V, Leitzmann M, Tjønneland A, Severi G, Mancini FR, Dong C, Kaaks R, Fortner RT, Bergmann MM, Boeing H, Trichopoulou A, Karakatsani A, Peppa E, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Bueno-de-Mesquita HB, Skeie G, Merino S, Ros RZ, Sánchez MJ, Amiano P, Huerta JM, Barricarte A, Sjöberg K, Ohlsson B, Nyström H, Werner M, Perez-Cornago A, Schmidt JA, Freisling H, Scalbert A, Weiderpass E, Christakoudi S, Gunter MJ, Jenab M.
Stepien M, et al.
Int J Cancer. 2022 Apr 15;150(8):1255-1268. doi: 10.1002/ijc.33885. Epub 2022 Jan 11.
Int J Cancer. 2022.
PMID: 34843121
Free article.
Positive HCC risk associations were observed for the molar sum of all BAs (OR(doubling) = 2.30, 95% confidence intervals [CI]: 1.76-3.00), and choline- and taurine-conjugated BAs. Relative concentrations of BAs showed positive HCC risk associations for glycoh …
Positive HCC risk associations were observed for the molar sum of all BAs (OR(doubling) = 2.30, 95% confidence intervals [CI]: 1.76-3 …