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GPR18 drives FAAH inhibition-induced neuroprotection against HIV-1 Tat-induced neurodegeneration.
Hermes DJ, Yadav-Samudrala BJ, Xu C, Paniccia JE, Meeker RB, Armstrong ML, Reisdorph N, Cravatt BF, Mackie K, Lichtman AH, Ignatowska-Jankowska BM, Lysle DT, Fitting S. Hermes DJ, et al. Among authors: yadav samudrala bj. Exp Neurol. 2021 Jul;341:113699. doi: 10.1016/j.expneurol.2021.113699. Epub 2021 Mar 15. Exp Neurol. 2021. PMID: 33736974 Free PMC article.
Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms.
Xu C, Yadav-Samudrala BJ, Xu C, Nath B, Mistry T, Jiang W, Niphakis MJ, Cravatt BF, Mukhopadhyay S, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. Xu C, et al. Among authors: yadav samudrala bj. Cells. 2022 Mar 2;11(5):857. doi: 10.3390/cells11050857. Cells. 2022. PMID: 35269478 Free PMC article.
Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat.
League AF, Gorman BL, Hermes DJ, Johnson CT, Jacobs IR, Yadav-Samudrala BJ, Poklis JL, Niphakis MJ, Cravatt BF, Lichtman AH, Ignatowska-Jankowska BM, Fitting S. League AF, et al. Among authors: yadav samudrala bj. Front Neurol. 2021 Aug 16;12:651272. doi: 10.3389/fneur.2021.651272. eCollection 2021. Front Neurol. 2021. PMID: 34484091 Free PMC article.
Acute Effects of Monoacylglycerol Lipase Inhibitor ABX1431 on Neuronal Hyperexcitability, Nociception, Locomotion, and the Endocannabinoid System in HIV-1 Tat Male Mice.
Yadav-Samudrala BJ, Ravula HP, Barmada KM, Dodson H, Poklis JL, Ignatowska-Jankowska BM, Lichtman AH, Reissner KJ, Fitting S. Yadav-Samudrala BJ, et al. Cannabis Cannabinoid Res. 2024 Feb 23. doi: 10.1089/can.2023.0247. Online ahead of print. Cannabis Cannabinoid Res. 2024. PMID: 38394322
Escalating morphine dosing in HIV-1 Tat transgenic mice with sustained Tat exposure reveals an allostatic shift in neuroinflammatory regulation accompanied by increased neuroprotective non-endocannabinoid lipid signaling molecules and amino acids.
Hermes DJ, Jacobs IR, Key MC, League AF, Yadav-Samudrala BJ, Xu C, McLane VD, Nass SR, Jiang W, Meeker RB, Ignatowska-Jankowska BM, Lichtman AH, Li Z, Wu Z, Yuan H, Knapp PE, Hauser KF, Fitting S. Hermes DJ, et al. Among authors: yadav samudrala bj. J Neuroinflammation. 2020 Nov 18;17(1):345. doi: 10.1186/s12974-020-01971-6. J Neuroinflammation. 2020. PMID: 33208151 Free PMC article.