Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1955 1
1959 1
1961 1
1968 1
1983 1
1990 1
1993 1
1999 1
2002 1
2004 2
2006 2
2007 2
2008 2
2009 2
2010 2
2011 4
2012 2
2013 2
2014 6
2015 3
2016 11
2017 6
2018 9
2019 14
2020 10
2021 10
2022 13
2023 23
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

124 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: Rivza
Page 1
β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway.
Jung TW, Park HS, Choi GH, Kim D, Lee T. Jung TW, et al. J Biomed Sci. 2018 Mar 28;25(1):27. doi: 10.1186/s12929-018-0431-7. J Biomed Sci. 2018. PMID: 29592806 Free PMC article.
Previous reports have also demonstrated strong anti-inflammatory effects of BAIBA. METHODS: We used BAIBA treated fully differentiated 3T3T-L1 mouse adipocytes to investigate the effects of exogenous BAIBA on inflammation and insulin signaling in adipocytes. …
Previous reports have also demonstrated strong anti-inflammatory effects of BAIBA. METHODS: We used BAIBA treated fully differ …
Regulation of Skeletal Muscle Function by Amino Acids.
Kamei Y, Hatazawa Y, Uchitomi R, Yoshimura R, Miura S. Kamei Y, et al. Nutrients. 2020 Jan 19;12(1):261. doi: 10.3390/nu12010261. Nutrients. 2020. PMID: 31963899 Free PMC article. Review.
The metabolite of valine (another BCAA), beta-aminoisobutyric acid (BAIBA), is increased by exercise, is secreted by the skeletal muscle, and acts on other tissues, such as white adipose tissue, to increase energy expenditure. ...
The metabolite of valine (another BCAA), beta-aminoisobutyric acid (BAIBA), is increased by exercise, is secreted by the skeletal mus …
Signaling metabolite β-aminoisobutyric acid as a metabolic regulator, biomarker, and potential exercise pill.
Yi X, Yang Y, Li T, Li M, Yao T, Hu G, Wan G, Chang B. Yi X, et al. Front Endocrinol (Lausanne). 2023 May 29;14:1192458. doi: 10.3389/fendo.2023.1192458. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37313446 Free PMC article. Review.
BAIBA is produced during exercise and is involved in the exercise response. ...Further, BAIBA has been confirmed to participate in the diagnosis and prevention of diseases as an important biological marker of disease. ...
BAIBA is produced during exercise and is involved in the exercise response. ...Further, BAIBA has been confirmed to participat …
The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review.
Gonzalez-Gil AM, Elizondo-Montemayor L. Gonzalez-Gil AM, et al. Nutrients. 2020 Jun 26;12(6):1899. doi: 10.3390/nu12061899. Nutrients. 2020. PMID: 32604889 Free PMC article. Review.
In this review, we explain the potential role of these exercise-inducible factors, namely myokines, such as irisin, IL-6, IL-15, METRNL, BAIBA, and myostatin, and hepatokines, in particular selenoprotein P, fetuin A, FGF21, ANGPTL4, and follistatin. ...
In this review, we explain the potential role of these exercise-inducible factors, namely myokines, such as irisin, IL-6, IL-15, METRNL, …
Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment.
Granot-Hershkovitz E, Spitzer B, Yang Y, Tarraf W, Yu B, Boerwinkle E, Fornage M, Mosley TH, DeCarli C, Kristal BS, González HM, Sofer T. Granot-Hershkovitz E, et al. Transl Psychiatry. 2023 Apr 29;13(1):140. doi: 10.1038/s41398-023-02437-y. Transl Psychiatry. 2023. PMID: 37120436 Free PMC article.
We first performed a GWAS for the MCI-MRS and BAIBA, in Hispanic/Latino adults (n = 3890) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). We identified ten independent genome-wide significant (p value <5 10(-8)) variants associated with MCI-MRS or …
We first performed a GWAS for the MCI-MRS and BAIBA, in Hispanic/Latino adults (n = 3890) from the Hispanic Community Health Study/St …
Bone-Muscle Mutual Interactions.
Lara-Castillo N, Johnson ML. Lara-Castillo N, et al. Curr Osteoporos Rep. 2020 Aug;18(4):408-421. doi: 10.1007/s11914-020-00602-6. Curr Osteoporos Rep. 2020. PMID: 32519283 Free PMC article. Review.
Several signaling factors produced by muscle and bone have emerged as potential mediators of these biochemical/molecular interactions. These include muscle factors such as myostatin, Irisin, BAIBA, IL-6, and the IGF family and the bone factors FGF-23, Wnt1 and Wnt3a, PGE2, …
Several signaling factors produced by muscle and bone have emerged as potential mediators of these biochemical/molecular interactions. These …
beta-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor.
Kitase Y, Vallejo JA, Gutheil W, Vemula H, Jähn K, Yi J, Zhou J, Brotto M, Bonewald LF. Kitase Y, et al. Cell Rep. 2018 Feb 6;22(6):1531-1544. doi: 10.1016/j.celrep.2018.01.041. Cell Rep. 2018. PMID: 29425508 Free PMC article.
The exercise-induced muscle factor beta-aminoisobutyric acid (BAIBA) plays a critical role in the browning of white fat and in insulin resistance. ...The protective effect of BAIBA was lost with age, not due to loss of the muscle capacity to produce BAIBA but …
The exercise-induced muscle factor beta-aminoisobutyric acid (BAIBA) plays a critical role in the browning of white fat and in insuli …
Elevated circulating level of beta-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors.
Katano S, Yano T, Kouzu H, Nagaoka R, Numazawa R, Yamano K, Fujisawa Y, Ohori K, Nagano N, Fujito T, Nishikawa R, Ohwada W, Katayose M, Sato T, Kuno A, Furuhashi M. Katano S, et al. Cardiovasc Diabetol. 2022 Dec 20;21(1):285. doi: 10.1186/s12933-022-01727-x. Cardiovasc Diabetol. 2022. PMID: 36539818 Free PMC article.
Analyses in patients in whom plasma BAIBA was detected showed that plasma BAIBA concentration was significantly higher in patients receiving an SGLT2i than in patients not receiving an SGLT2i (6.76 4.72 vs. 4.56 2.93 nmol/ml, p = 0.03). ...CONCLUSION: SGLT2i use is …
Analyses in patients in whom plasma BAIBA was detected showed that plasma BAIBA concentration was significantly higher in pati …
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.
Zhang Z, Li X, Guo J, He B, Wu L, Yang R, Li X, Fang D, Yang X, Yang D, Wang F, Tang M, Han Y, Jose PA, Wang H, Zeng C. Zhang Z, et al. Mol Med. 2023 Dec 4;29(1):164. doi: 10.1186/s10020-023-00729-z. Mol Med. 2023. PMID: 38049750 Free PMC article.
Additionally, we demonstrated that the Nrf-2 signaling pathway is key to the inhibitory effect of L-BAIBA on ferroptosis in A549 and BEAS-2B cells. L-BAIBA can induce the nuclear translocation of Nrf-2. Interfering with the expression of Nrf-2 eliminated the protect …
Additionally, we demonstrated that the Nrf-2 signaling pathway is key to the inhibitory effect of L-BAIBA on ferroptosis in A549 and …
An Overview of the Molecular Mechanisms Contributing to Musculoskeletal Disorders in Chronic Liver Disease: Osteoporosis, Sarcopenia, and Osteoporotic Sarcopenia.
Yang YJ, Kim DJ. Yang YJ, et al. Int J Mol Sci. 2021 Mar 5;22(5):2604. doi: 10.3390/ijms22052604. Int J Mol Sci. 2021. PMID: 33807573 Free PMC article. Review.
The bidirectional crosstalk between muscle and bone through myostatin, irisin, beta-aminoisobutyric acid (BAIBA), osteocalcin, as well as the activation of the RANK and the Wnt/beta-catenin pathways are associated with osteosarcopenia. ...
The bidirectional crosstalk between muscle and bone through myostatin, irisin, beta-aminoisobutyric acid (BAIBA), osteocalcin, as wel …
124 results