Primary cutaneous mucormycosis (zygomycosis) caused by Apophysomyces elegans

Indian J Dermatol Venereol Leprol. 2008 Jul-Aug;74(4):367-70. doi: 10.4103/0378-6323.42912.

Abstract

A 53 year-old male diabetic presented with a month-old, painful ulcer with necrotic margins over the right thigh. Wound debridement was done twice and the ulcer showed recurrent growth of a white, cottony filamentous structure. Cutaneous mucormycosis was suspected and confirmed by histopathology and a culture isolate of Apophysomyces elegans . The patient was treated with liposomal amphotericin-B and itraconazole followed by partial thickness skin grafting, and then discharged after being prescribed posaconazole syrup for three weeks. Regular follow-up was done and during the last visit after six months following discharge, the ulcer was found to have healed well with no recurrence of the fungus.

Publication types

  • Case Reports

MeSH terms

  • Accidents, Traffic
  • Antifungal Agents / therapeutic use
  • Debridement
  • Dermatomycoses / etiology
  • Dermatomycoses / microbiology*
  • Dermatomycoses / therapy
  • Diabetes Complications
  • Drug Therapy, Combination
  • Humans
  • Male
  • Middle Aged
  • Mucorales / isolation & purification
  • Mucormycosis / etiology
  • Mucormycosis / microbiology*
  • Mucormycosis / therapy
  • Recurrence
  • Skin / microbiology
  • Skin Transplantation
  • Thigh

Substances

  • Antifungal Agents