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Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B (PIB-PET) and cerebrospinal fluid phosphorylated tau (phospho-tau) concentrations. ...
Secondary outcome measures included findings on positron-emission tomographic amyloid imaging with the use of Pittsburgh compound B ( …
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy.
Yamin R, Jones AT, Hoffmann HH, Schäfer A, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S. Yamin R, et al. Nature. 2021 Nov;599(7885):465-470. doi: 10.1038/s41586-021-04017-w. Epub 2021 Sep 21. Nature. 2021. PMID: 34547765 Free PMC article.
Fc-engineered antibody therapeutics with improved efficacy against COVID-19.
Yamin R, Jones AT, Hoffmann HH, Kao KS, Francis RL, Sheahan TP, Baric RS, Rice CM, Ravetch JV, Bournazos S. Yamin R, et al. Res Sq [Preprint]. 2021 May 27:rs.3.rs-555612. doi: 10.21203/rs.3.rs-555612/v1. Res Sq. 2021. PMID: 34075373 Free PMC article. Updated. Preprint.
BNT162b2 vaccination effectively prevents the rapid rise of SARS-CoV-2 variant B.1.1.7 in high-risk populations in Israel.
Munitz A, Yechezkel M, Dickstein Y, Yamin D, Gerlic M. Munitz A, et al. Cell Rep Med. 2021 May 18;2(5):100264. doi: 10.1016/j.xcrm.2021.100264. Epub 2021 Apr 18. Cell Rep Med. 2021. PMID: 33899031 Free PMC article.
Since the emergence of the SARS-CoV-2 pandemic, various genetic variants have been described. The B.1.1.7 variant, which emerged in England during December 2020, is associated with increased infectivity. ...Despite the rapid increase in viral spread, focused RT-PCR testing …
Since the emergence of the SARS-CoV-2 pandemic, various genetic variants have been described. The B.1.1.7 variant, which emerged in E …
Hexaferrocenium tri[hexa(isothiocyanato)iron(III)] trihydroxonium complex as a new DNA intercalator for electrochemical DNA biosensor.
Ariffin EY, Zakariah EI, Ruslin F, Kassim M, Yamin BM, Heng LY, Hasbullah SA. Ariffin EY, et al. Sci Rep. 2021 Apr 12;11(1):7883. doi: 10.1038/s41598-021-86939-z. Sci Rep. 2021. PMID: 33846405 Free PMC article.
The UV-Vis DNA titrations with this compound showed hypochromism and redshift at 250 nm with increasing DNA concentrations. The binding constant (K(b)) for HexaFc complex towards CT-DNA (calf-thymus DNA) was 3.1 10(4) M(-1), indicated intercalator behaviour of the c …
The UV-Vis DNA titrations with this compound showed hypochromism and redshift at 250 nm with increasing DNA concentrations. The binding cons …
Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial.
Vinson DR, Mark DG, Chettipally UK, Huang J, Rauchwerger AS, Reed ME, Lin JS, Kene MV, Wang DH, Sax DR, Pleshakov TS, McLachlan ID, Yamin CK, Elms AR, Iskin HR, Vemula R, Yealy DM, Ballard DW; eSPEED Investigators of the KP CREST Network. Vinson DR, et al. Ann Intern Med. 2018 Dec 18;169(12):855-865. doi: 10.7326/M18-1206. Epub 2018 Nov 13. Ann Intern Med. 2018. PMID: 30422263 Clinical Trial.
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin.
Brines M, Patel NS, Villa P, Brines C, Mennini T, De Paola M, Erbayraktar Z, Erbayraktar S, Sepodes B, Thiemermann C, Ghezzi P, Yamin M, Hand CC, Xie QW, Coleman T, Cerami A. Brines M, et al. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10925-30. doi: 10.1073/pnas.0805594105. Epub 2008 Aug 1. Proc Natl Acad Sci U S A. 2008. PMID: 18676614 Free PMC article.
Further, this peptide simulating the aqueous surface of helix B also exhibits EPO's trophic effects by accelerating wound healing and augmenting cognitive function in rodents. As anticipated, neither helix B nor the 11-aa peptide is erythropoietic in vitro or in viv …
Further, this peptide simulating the aqueous surface of helix B also exhibits EPO's trophic effects by accelerating wound healing and …
14 results