Maternal vitamin B(12) deficiency in rats alters DNA methylation in metabolically important genes in their offspring.
Tanwar VS, Ghosh S, Sati S, Ghose S, Kaur L, Kumar KA, Shamsudheen KV, Patowary A, Singh M, Jyothi V, Kommineni P, Sivasubbu S, Scaria V, Raghunath M, Mishra R, Chandak GR, Sengupta S.
Tanwar VS, et al.
Mol Cell Biochem. 2020 May;468(1-2):83-96. doi: 10.1007/s11010-020-03713-x. Epub 2020 Mar 18.
Mol Cell Biochem. 2020.
PMID: 32189172
In this study, we have investigated the effects of maternal B(12) deficiency on genome-wide DNA methylation profile of the offspring and the effect of rehabilitation of mothers with B(12) at conception. We have performed methylated DNA immunoprecipitation sequencing …
In this study, we have investigated the effects of maternal B(12) deficiency on genome-wide DNA methylation profile of the offspring …