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Page 1
MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α.
Cell Rep. 2023 Feb 28;42(2):112066. doi: 10.1016/j.celrep.2023.112066. Epub 2023 Feb 3.
Cell Rep. 2023.
PMID: 36739529
Free article.
Neuroplastin Modulates Anti-inflammatory Effects of MANF.
Yagi T, Asada R, Kanekura K, Eesmaa A, Lindahl M, Saarma M, Urano F.
Yagi T, et al. Among authors: eesmaa a.
iScience. 2020 Nov 17;23(12):101810. doi: 10.1016/j.isci.2020.101810. eCollection 2020 Dec 18.
iScience. 2020.
PMID: 33299977
Free PMC article.
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CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival.
Eesmaa A, Yu LY, Göös H, Danilova T, Nõges K, Pakarinen E, Varjosalo M, Lindahl M, Lindholm P, Saarma M.
Eesmaa A, et al.
Int J Mol Sci. 2022 Aug 22;23(16):9489. doi: 10.3390/ijms23169489.
Int J Mol Sci. 2022.
PMID: 36012764
Free PMC article.
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The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor.
Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M.
Eesmaa A, et al.
J Biol Chem. 2021 Jan-Jun;296:100295. doi: 10.1016/j.jbc.2021.100295. Epub 2021 Jan 15.
J Biol Chem. 2021.
PMID: 33460650
Free PMC article.
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Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.
Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M.
Albert K, et al. Among authors: eesmaa a.
Mol Ther. 2021 Sep 1;29(9):2821-2840. doi: 10.1016/j.ymthe.2021.04.035. Epub 2021 May 1.
Mol Ther. 2021.
PMID: 33940158
Free PMC article.
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Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's Disease.
Garea-Rodríguez E, Eesmaa A, Lindholm P, Schlumbohm C, König J, Meller B, Krieglstein K, Helms G, Saarma M, Fuchs E.
Garea-Rodríguez E, et al. Among authors: eesmaa a.
PLoS One. 2016 Feb 22;11(2):e0149776. doi: 10.1371/journal.pone.0149776. eCollection 2016.
PLoS One. 2016.
PMID: 26901822
Free PMC article.
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Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5' exon usage and splicing.
Sepp M, Kannike K, Eesmaa A, Urb M, Timmusk T.
Sepp M, et al. Among authors: eesmaa a.
PLoS One. 2011;6(7):e22138. doi: 10.1371/journal.pone.0022138. Epub 2011 Jul 15.
PLoS One. 2011.
PMID: 21789225
Free PMC article.
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