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Page 1
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.
J Biol Chem. 2021 Jan-Jun;296:100056. doi: 10.1074/jbc.RA120.015585. Epub 2020 Nov 24.
J Biol Chem. 2021.
PMID: 33172888
Free PMC article.
Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance.
Wisinski JA, Reuter A, Peter DC, Schaid MD, Fenske RJ, Kimple ME.
Wisinski JA, et al. Among authors: reuter a.
Am J Physiol Endocrinol Metab. 2021 Oct 1;321(4):E479-E489. doi: 10.1152/ajpendo.00051.2021. Epub 2021 Jul 6.
Am J Physiol Endocrinol Metab. 2021.
PMID: 34229444
Free PMC article.
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Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes.
Schaid MD, Zhu Y, Richardson NE, Patibandla C, Ong IM, Fenske RJ, Neuman JC, Guthery E, Reuter A, Sandhu HK, Fuller MH, Cox ED, Davis DB, Layden BT, Brasier AR, Lamming DW, Ge Y, Kimple ME.
Schaid MD, et al. Among authors: reuter a.
Metabolites. 2021 Jan 16;11(1):58. doi: 10.3390/metabo11010058.
Metabolites. 2021.
PMID: 33467110
Free PMC article.
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Human Islet Expression Levels of Prostaglandin E2 Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity.
Truchan NA, Fenske RJ, Sandhu HK, Weeks AM, Patibandla C, Wancewicz B, Pabich S, Reuter A, Harrington JM, Brill AL, Peter DC, Nall R, Daniels M, Punt M, Kaiser CE, Cox ED, Ge Y, Davis DB, Kimple ME.
Truchan NA, et al. Among authors: reuter a.
ACS Pharmacol Transl Sci. 2021 Jun 16;4(4):1338-1348. doi: 10.1021/acsptsci.1c00045. eCollection 2021 Aug 13.
ACS Pharmacol Transl Sci. 2021.
PMID: 34423270
Free PMC article.
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The prostaglandin E2 EP3 receptor has disparate effects on islet insulin secretion and content in β-cells in a high-fat diet-induced mouse model of obesity.
Neuman JC, Reuter A, Carbajal KA, Schaid MD, Kelly G, Connors K, Kaiser C, Krause J, Hurley LD, Olvera A, Davis DB, Wisinski JA, Gannon M, Kimple ME.
Neuman JC, et al. Among authors: reuter a.
Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E567-E576. doi: 10.1152/ajpendo.00061.2023. Epub 2024 Mar 13.
Am J Physiol Endocrinol Metab. 2024.
PMID: 38477664
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