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Year Number of Results
2003 2
2004 1
2005 1
2006 2
2011 2
2014 2
2016 1
2018 1
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2020 2
2021 4
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2023 2
2024 0

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Page 1
Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model.
Zancanella V, Vallès A, Liefhebber JMP, Paerels L, Tornero CV, Wattimury H, van der Zon T, van Rooijen K, Golinska M, Grevelink T, Ehlert E, Pieterman EJ, Keijzer N, Princen HMG, Stokman G, Liu YP. Zancanella V, et al. Among authors: valles a. Mol Ther Nucleic Acids. 2023 Apr 7;32:454-467. doi: 10.1016/j.omtn.2023.04.004. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37168797 Free PMC article.
Widespread and sustained target engagement in Huntington's disease minipigs upon intrastriatal microRNA-based gene therapy.
Vallès A, Evers MM, Stam A, Sogorb-Gonzalez M, Brouwers C, Vendrell-Tornero C, Acar-Broekmans S, Paerels L, Klima J, Bohuslavova B, Pintauro R, Fodale V, Bresciani A, Liscak R, Urgosik D, Starek Z, Crha M, Blits B, Petry H, Ellederova Z, Motlik J, van Deventer S, Konstantinova P. Vallès A, et al. Sci Transl Med. 2021 Apr 7;13(588):eabb8920. doi: 10.1126/scitranslmed.abb8920. Sci Transl Med. 2021. PMID: 33827977
miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.
Nobre RJ, Lobo DD, Henriques C, Duarte SP, Lopes SM, Silva AC, Lopes MM, Mariet F, Schwarz LK, Baatje MS, Ferreira V, Vallès A, Pereira de Almeida L, Evers MM, Toonen LJA. Nobre RJ, et al. Among authors: valles a. Nucleic Acid Ther. 2022 Jun;32(3):194-205. doi: 10.1089/nat.2021.0020. Epub 2021 Dec 7. Nucleic Acid Ther. 2022. PMID: 34878314 Free PMC article.
Secreted therapeutics: monitoring durability of microRNA-based gene therapies in the central nervous system.
Sogorb-Gonzalez M, Vendrell-Tornero C, Snapper J, Stam A, Keskin S, Miniarikova J, Spronck EA, de Haan M, Nieuwland R, Konstantinova P, van Deventer SJ, Evers MM, Vallès A. Sogorb-Gonzalez M, et al. Among authors: valles a. Brain Commun. 2021 Apr 1;3(2):fcab054. doi: 10.1093/braincomms/fcab054. eCollection 2021. Brain Commun. 2021. PMID: 34704020 Free PMC article.
White matter structure and myelin-related gene expression alterations with experience in adult rats.
Sampaio-Baptista C, Vallès A, Khrapitchev AA, Akkermans G, Winkler AM, Foxley S, Sibson NR, Roberts M, Miller K, Diamond ME, Martens GJM, De Weerd P, Johansen-Berg H. Sampaio-Baptista C, et al. Among authors: valles a. Prog Neurobiol. 2020 Apr;187:101770. doi: 10.1016/j.pneurobio.2020.101770. Epub 2020 Jan 27. Prog Neurobiol. 2020. PMID: 32001310 Free PMC article.
24 results