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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1976 3
1977 4
1978 4
1979 4
1980 5
1981 7
1982 3
1983 6
1984 2
1985 2
1986 2
1987 2
1989 3
1990 1
1991 1
1992 2
1993 4
1994 5
1995 6
1996 4
1997 8
1998 9
1999 4
2000 11
2001 5
2002 8
2003 8
2004 14
2005 18
2006 20
2007 11
2008 13
2009 14
2010 18
2011 17
2012 21
2013 25
2014 35
2015 31
2016 28
2017 39
2018 32
2019 36
2020 52
2021 74
2022 69
2023 55
2024 28

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699 results

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The following term was not found in PubMed: Gospodini
Page 1
Aspartoacylase suppresses prostate cancer progression by blocking LYN activation.
Weng H, Xiong KP, Wang W, Qian KY, Yuan S, Wang G, Yu F, Luo J, Lu MX, Yang ZH, Liu T, Huang X, Zheng H, Wang XH. Weng H, et al. Mil Med Res. 2023 Jun 5;10(1):25. doi: 10.1186/s40779-023-00460-0. Mil Med Res. 2023. PMID: 37271807 Free PMC article.
The inhibitory role of ASPA in PCa was further confirmed using orthotopic and tumor-bearing mouse models. ...Moreover, we observed an inverse relationship between ASPA expression and LYN activity in clinical PCa samples, suggesting a potential regulatory role of …
The inhibitory role of ASPA in PCa was further confirmed using orthotopic and tumor-bearing mouse models. ...Moreover, we observed an …
Canavan Disease.
Nagy A, Bley AE, Eichler F. Nagy A, et al. 1999 Sep 16 [updated 2023 Dec 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 1999 Sep 16 [updated 2023 Dec 21]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301412 Free Books & Documents. Review.
The molecular diagnosis is established in an individual with suggestive clinical findings and biallelic ASPA pathogenic variants identified by molecular genetic testing. ...Once the ASPA pathogenic variants have been identified in an affected family member, carrier …
The molecular diagnosis is established in an individual with suggestive clinical findings and biallelic ASPA pathogenic variants iden …
Expression of aspartoacylase (ASPA) and Canavan disease.
Sommer A, Sass JO. Sommer A, et al. Gene. 2012 Sep 1;505(2):206-10. doi: 10.1016/j.gene.2012.06.036. Epub 2012 Jun 28. Gene. 2012. PMID: 22750302
All ASPA mutants tested (ASPA Arg168His, ASPA Pro181Thr, ASPA Tyr288Cys, ASPA Phe295Ser, and ASPA Ala305Glu) showed loss of ASPA activity, which can be explained by the intramolecular effects of the mutations in the enzyme. ...Usin …
All ASPA mutants tested (ASPA Arg168His, ASPA Pro181Thr, ASPA Tyr288Cys, ASPA Phe295Ser, and ASPA …
Editorial: "AAV Gene Therapy: Immunology and Immunotherapeutics".
Martinez-Navio JM, Paulk NK, Gao G. Martinez-Navio JM, et al. Front Immunol. 2021 Dec 21;12:822389. doi: 10.3389/fimmu.2021.822389. eCollection 2021. Front Immunol. 2021. PMID: 34992614 Free PMC article. No abstract available.
The pathogenesis of, and pharmacological treatment for, Canavan disease.
Wei H, Moffett JR, Amanat M, Fatemi A, Tsukamoto T, Namboodiri AM, Slusher BS. Wei H, et al. Drug Discov Today. 2022 Sep;27(9):2467-2483. doi: 10.1016/j.drudis.2022.05.019. Epub 2022 May 27. Drug Discov Today. 2022. PMID: 35636725 Review.
Canavan disease (CD) is an inherited leukodystrophy resulting from mutations in the gene encoding aspartoacylase (ASPA). ASPA is highly expressed in oligodendrocytes and catalyzes the cleavage of N-acetylaspartate (NAA) to produce aspartate and acetate. In this revi …
Canavan disease (CD) is an inherited leukodystrophy resulting from mutations in the gene encoding aspartoacylase (ASPA). ASPA …
Allogeneic hematopoietic stem cell transplantation for NK/T-cell lymphoma: an international collaborative analysis.
Berning P, Schmitz N, Ngoya M, Finel H, Boumendil A, Wang F, Huang XJ, Hermine O, Philippe L, Couronné L, Jaccard A, Liu D, Wu D, Reinhardt HC, Chalandon Y, Wagner-Drouet E, Kwon M, Zhang X, Carpenter B, Yakoub-Agha I, Wulf G, López-Jiménez J, Sanz J, Labussière-Wallet H, Shimoni A, Dreger P, Sureda A, Kim WS, Glass B. Berning P, et al. Leukemia. 2023 Jul;37(7):1511-1520. doi: 10.1038/s41375-023-01924-x. Epub 2023 May 8. Leukemia. 2023. PMID: 37157017 Free PMC article.
Patients (pts) with relapsed/refractory disease after Asparaginase (ASPA)-based chemotherapy have a dismal prognosis. To better define the role of allogeneic hematopoietic stem cell transplantation (allo-HSCT), we conducted a retrospective analysis of data shared with the …
Patients (pts) with relapsed/refractory disease after Asparaginase (ASPA)-based chemotherapy have a dismal prognosis. To better defin …
ASPA: Advanced Strong Pseudonym based Authentication in Intelligent Transport System.
Ali QE, Ahmad N, Malik AH, Rehman WU, Din AU, Ali G. Ali QE, et al. PLoS One. 2019 Aug 22;14(8):e0221213. doi: 10.1371/journal.pone.0221213. eCollection 2019. PLoS One. 2019. PMID: 31437260 Free PMC article.
ASPA only allows vehicles with valid pseudonyms to communicate in ITS. ...The empirical results prove that ASPA is robust and efficient with low computational cost, overhead ratio, average latency, and an increased delivery ratio....
ASPA only allows vehicles with valid pseudonyms to communicate in ITS. ...The empirical results prove that ASPA is robust and …
The AgI/II family adhesin AspA is required for respiratory infection by Streptococcus pyogenes.
Franklin L, Nobbs AH, Bricio-Moreno L, Wright CJ, Maddocks SE, Sahota JS, Ralph J, O'Connor M, Jenkinson HF, Kadioglu A. Franklin L, et al. PLoS One. 2013 Apr 30;8(4):e62433. doi: 10.1371/journal.pone.0062433. Print 2013. PLoS One. 2013. PMID: 23638083 Free PMC article.
We demonstrated the requirement for AspA in colonization of the respiratory tract. AspA mutants were cleared from the respiratory tract and were deficient in adherence to epithelial cells, and susceptible to phagocytosis. Expression of AspA in the surrogate h …
We demonstrated the requirement for AspA in colonization of the respiratory tract. AspA mutants were cleared from the respirat …
699 results