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Therapeutic targeting of regulatory T cells in cancer.
Shan F, Somasundaram A, Bruno TC, Workman CJ, Vignali DAA. Shan F, et al. Among authors: somasundaram a. Trends Cancer. 2022 Nov;8(11):944-961. doi: 10.1016/j.trecan.2022.06.008. Epub 2022 Jul 16. Trends Cancer. 2022. PMID: 35853825 Free PMC article. Review.
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.
Liu C, Somasundaram A, Manne S, Gocher AM, Szymczak-Workman AL, Vignali KM, Scott EN, Normolle DP, John Wherry E, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Liu C, et al. Among authors: somasundaram a. Nat Immunol. 2020 Sep;21(9):1010-1021. doi: 10.1038/s41590-020-0733-2. Epub 2020 Jul 13. Nat Immunol. 2020. PMID: 32661362 Free PMC article.
The Role of the Estrogen Pathway in the Tumor Microenvironment.
Rothenberger NJ, Somasundaram A, Stabile LP. Rothenberger NJ, et al. Among authors: somasundaram a. Int J Mol Sci. 2018 Feb 19;19(2):611. doi: 10.3390/ijms19020611. Int J Mol Sci. 2018. PMID: 29463044 Free PMC article. Review.
Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.
Chuckran CA, Cillo AR, Moskovitz J, Overacre-Delgoffe A, Somasundaram AS, Shan F, Magnon GC, Kunning SR, Abecassis I, Zureikat AH, Luketich J, Pennathur A, Sembrat J, Rojas M, Merrick DT, Taylor SE, Orr B, Modugno F, Buckanovich R, Schoen RE, Kim S, Duvvuri U, Zeh H, Edwards R, Kirkwood JM, Coffman L, Ferris RL, Bruno TC, Vignali DAA. Chuckran CA, et al. Among authors: somasundaram as. Sci Transl Med. 2021 Dec 8;13(623):eabf8495. doi: 10.1126/scitranslmed.abf8495. Epub 2021 Dec 8. Sci Transl Med. 2021. PMID: 34878821 Free PMC article.
19 results