Adventitial alterations are the main features in pulmonary artery remodeling due to long-term chronic intermittent hypobaric hypoxia in rats.
Brito J, Siques P, Arribas SM, López de Pablo AL, González MC, Naveas N, Arriaza K, Flores K, León-Velarde F, Pulido R, Ordenes S, López MR.
Brito J, et al.
Biomed Res Int. 2015;2015:169841. doi: 10.1155/2015/169841. Epub 2015 Feb 8.
Biomed Res Int. 2015.
PMID: 25738150
Free PMC article.
Rats were subjected to chronic hypoxia (CH, n = 9) and long-term intermittent hypoxia (CIH2x2; 2 days of hypoxia/2 days of normoxia, n = 10) in a chamber (428 Torr, 4,600 m of altitude) for 46 days and compared to rats under normoxia (NX, n = 10). ...
Rats were subjected to chronic hypoxia (CH, n = 9) and long-term intermittent hypoxia (CIH2x2; 2 days of hypoxia/2 days of normoxia, n = 10) …