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Structure-Based Design and Synthesis of Stapled 10Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases.
Lamouroux A, Tournier M, Iaculli D, Caufriez A, Rusiecka OM, Martin C, Bes V, Carpio LE, Girardin Y, Loris R, Tabernilla A, Molica F, Gozalbes R, Mayán MD, Vinken M, Kwak BR, Ballet S. Lamouroux A, et al. J Med Chem. 2023 Sep 28;66(18):13086-13102. doi: 10.1021/acs.jmedchem.3c01116. Epub 2023 Sep 13. J Med Chem. 2023. PMID: 37703077 Free PMC article.
Effects of Drugs Formerly Suggested for COVID-19 Repurposing on Pannexin1 Channels.
Caufriez A, Tabernilla A, Van Campenhout R, Cooreman A, Leroy K, Sanz Serrano J, Kadam P, Dos Santos Rodrigues B, Lamouroux A, Ballet S, Vinken M. Caufriez A, et al. Among authors: lamouroux a. Int J Mol Sci. 2022 May 18;23(10):5664. doi: 10.3390/ijms23105664. Int J Mol Sci. 2022. PMID: 35628472 Free PMC article.
Impact of doubling peptide length on in vivo hydrogel stability and sustained drug release.
Heremans J, Chevillard L, Mannes M, Mangialetto J, Leroy K, White JF, Lamouroux A, Vinken M, Gardiner J, Van Mele B, Van den Brande N, Hoogenboom R, Madder A, Caveliers V, Mégarbane B, Hernot S, Ballet S, Martin C. Heremans J, et al. Among authors: lamouroux a. J Control Release. 2022 Oct;350:514-524. doi: 10.1016/j.jconrel.2022.08.027. Epub 2022 Sep 1. J Control Release. 2022. PMID: 35998769
Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure†.
Martin C, Gimenez LE, Williams SY, Jing Y, Wu Y, Hollanders C, Van der Poorten O, Gonzalez S, Van Holsbeeck K, Previti S, Lamouroux A, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Martin C, et al. Among authors: lamouroux a. J Med Chem. 2021 Jan 14;64(1):357-369. doi: 10.1021/acs.jmedchem.0c01620. Epub 2020 Nov 14. J Med Chem. 2021. PMID: 33190475
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design.
Gimenez LE, Martin C, Yu J, Hollanders C, Hernandez CC, Wu Y, Yao D, Han GW, Dahir NS, Wu L, Van der Poorten O, Lamouroux A, Mannes M, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Gimenez LE, et al. Among authors: lamouroux a. J Med Chem. 2024 Feb 22;67(4):2690-2711. doi: 10.1021/acs.jmedchem.3c01822. Epub 2024 Feb 12. J Med Chem. 2024. PMID: 38345933