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The following term was not found in PubMed: Kalapouti
Page 1
Structural analysis of the basal state of the Artemis:DNA-PKcs complex.
Watanabe G, Lieber MR, Williams DR. Watanabe G, et al. Nucleic Acids Res. 2022 Jul 22;50(13):7697-7720. doi: 10.1093/nar/gkac564. Nucleic Acids Res. 2022. PMID: 35801871 Free PMC article.
An activated state of Artemis in complex with DNA-PK was solved by cryo-EM recently, which showed Artemis bound to the DNA. ...We define a mutually exclusive binding site for Artemis and XRCC4 on DNA-PKcs and show that an XRCC4 peptide disrupts the Artemis …
An activated state of Artemis in complex with DNA-PK was solved by cryo-EM recently, which showed Artemis bound to the DNA. .. …
Becoming Artemis's Mother.
McKinley SK. McKinley SK. Ann Surg Open. 2021 Dec 21;3(1):e115. doi: 10.1097/AS9.0000000000000115. eCollection 2022 Mar. Ann Surg Open. 2021. PMID: 37600097 Free PMC article.
Gene Therapy for Artemis-Deficient SCID.
Pai SY. Pai SY. N Engl J Med. 2022 Dec 22;387(25):2382-2386. doi: 10.1056/NEJMe2213255. N Engl J Med. 2022. PMID: 36546634 No abstract available.
Dynamics of the Artemis and DNA-PKcs Complex in the Repair of Double-Strand Breaks.
Watanabe G, Lieber MR. Watanabe G, et al. J Mol Biol. 2022 Dec 15;434(23):167858. doi: 10.1016/j.jmb.2022.167858. Epub 2022 Oct 19. J Mol Biol. 2022. PMID: 36270581 Free PMC article. Review.
Nearly all broken DNA ends require trimming before they can be suitable for joining by ligation. Artemis is the major nuclease for this purpose. Artemis is tightly regulated by one of the largest protein kinases, which tethers Artemis to its surface. ...Given …
Nearly all broken DNA ends require trimming before they can be suitable for joining by ligation. Artemis is the major nuclease for th …
Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.
Ogana HA, Hurwitz S, Hsieh CL, Geng H, Müschen M, Bhojwani D, Wolf MA, Larocque J, Lieber MR, Kim YM. Ogana HA, et al. Front Cell Dev Biol. 2023 Mar 31;11:1134121. doi: 10.3389/fcell.2023.1134121. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37082620 Free PMC article.
Therefore, we evaluated four compounds (827171, 827032, 826941, and 825226), previously generated from a large Artemis targeted drug screen. A biochemical assay using a purified Artemis:DNA-PKcs complex shows that the Artemis inhibitors 827171, 827032, 826941 …
Therefore, we evaluated four compounds (827171, 827032, 826941, and 825226), previously generated from a large Artemis targeted drug …
Physical ARTEMIS:DNA-PKcs interaction is necessary for V(D)J recombination.
Niewolik D, Schwarz K. Niewolik D, et al. Nucleic Acids Res. 2022 Feb 28;50(4):2096-2110. doi: 10.1093/nar/gkac071. Nucleic Acids Res. 2022. PMID: 35150269 Free PMC article.
In ARTEMIS, specific mutations in two conserved regions affect interaction with DNA-PKcs. In combination they impair V(D)J recombination activity, independent of ARTEMIS autoinhibitory self-interaction between the ARTEMIS C-terminus and the N-terminal nucleas …
In ARTEMIS, specific mutations in two conserved regions affect interaction with DNA-PKcs. In combination they impair V(D)J recombinat …
Personalized diagnosis in suspected myocardial infarction.
Neumann JT, Twerenbold R, Ojeda F, Aldous SJ, Allen BR, Apple FS, Babel H, Christenson RH, Cullen L, Di Carluccio E, Doudesis D, Ekelund U, Giannitsis E, Greenslade J, Inoue K, Jernberg T, Kavsak P, Keller T, Lee KK, Lindahl B, Lorenz T, Mahler SA, Mills NL, Mokhtari A, Parsonage W, Pickering JW, Pemberton CJ, Reich C, Richards AM, Sandoval Y, Than MP, Toprak B, Troughton RW, Worster A, Zeller T, Ziegler A, Blankenberg S; ARTEMIS study group. Neumann JT, et al. Clin Res Cardiol. 2023 Sep;112(9):1288-1301. doi: 10.1007/s00392-023-02206-3. Epub 2023 May 2. Clin Res Cardiol. 2023. PMID: 37131096 Free PMC article.
RESULTS: Eleven routinely available variables including age, sex, cardiovascular risk factors, electrocardiography, and hs-cTn were included in the ARTEMIS models. In the validation and generalization cohorts, excellent discriminative performance was confirmed, superior to …
RESULTS: Eleven routinely available variables including age, sex, cardiovascular risk factors, electrocardiography, and hs-cTn were included …
[Science or politics?].
Schayan-Araghi K. Schayan-Araghi K. Ophthalmologe. 2021 Aug;118(8):859. doi: 10.1007/s00347-021-01433-1. Epub 2021 Jun 17. Ophthalmologe. 2021. PMID: 34137943 German. No abstract available.
Artemis, a novel guardian of the genome.
Dudásová Z, Chovanec M. Dudásová Z, et al. Neoplasma. 2003;50(5):311-8. Neoplasma. 2003. PMID: 14628082 Review.
Biochemical and structural properties of the Artemis proteins are reviewed and integrated into the processes of V(D)J recombination and NHEJ. A genomic caretaker function is assigned to Artemis....
Biochemical and structural properties of the Artemis proteins are reviewed and integrated into the processes of V(D)J recombination a …
Chromosome Instability Syndromes.
Kaseb H, Rayi A, Hozayen S. Kaseb H, et al. 2022 Sep 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2022 Sep 19. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 30725883 Free Books & Documents.
Other rare syndromes include ataxia telangiectasia-like disorder; immunodeficiency, centromeric instability, and facial anomalies syndromes; Cockayne syndrome; trichothiodystrophy; xeroderma pigmentosum; DNA ligase I deficiency; PMS2 deficiency; and DNA recombinase repair defects …
Other rare syndromes include ataxia telangiectasia-like disorder; immunodeficiency, centromeric instability, and facial anomalies syndromes; …
1,565 results