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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.
Fumagalli A, Oost KC, Kester L, Morgner J, Bornes L, Bruens L, Spaargaren L, Azkanaz M, Schelfhorst T, Beerling E, Heinz MC, Postrach D, Seinstra D, Sieuwerts AM, Martens JWM, van der Elst S, van Baalen M, Bhowmick D, Vrisekoop N, Ellenbroek SIJ, Suijkerbuijk SJE, Snippert HJ, van Rheenen J. Fumagalli A, et al. Cell Stem Cell. 2020 Apr 2;26(4):569-578.e7. doi: 10.1016/j.stem.2020.02.008. Epub 2020 Mar 12. Cell Stem Cell. 2020. PMID: 32169167 Free PMC article.
Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
Heinz MC, Peters NA, Oost KC, Lindeboom RGH, van Voorthuijsen L, Fumagalli A, van der Net MC, de Medeiros G, Hageman JH, Verlaan-Klink I, Borel Rinkes IHM, Liberali P, Gloerich M, van Rheenen J, Vermeulen M, Kranenburg O, Snippert HJG. Heinz MC, et al. Among authors: fumagalli a. Cancer Res. 2022 May 16;82(10):1953-1968. doi: 10.1158/0008-5472.CAN-21-0933. Cancer Res. 2022. PMID: 35570706 Free PMC article.
Liquid biopsy in colorectal cancer: Onward and upward.
Torresan S, de Scordilli M, Bortolot M, Di Nardo P, Foltran L, Fumagalli A, Guardascione M, Ongaro E, Puglisi F. Torresan S, et al. Among authors: fumagalli a. Crit Rev Oncol Hematol. 2024 Feb;194:104242. doi: 10.1016/j.critrevonc.2023.104242. Epub 2023 Dec 20. Crit Rev Oncol Hematol. 2024. PMID: 38128627 Review.
Active elimination of intestinal cells drives oncogenic growth in organoids.
Krotenberg Garcia A, Fumagalli A, Le HQ, Jackstadt R, Lannagan TRM, Sansom OJ, van Rheenen J, Suijkerbuijk SJE. Krotenberg Garcia A, et al. Among authors: fumagalli a. Cell Rep. 2021 Jul 6;36(1):109307. doi: 10.1016/j.celrep.2021.109307. Cell Rep. 2021. PMID: 34233177 Free PMC article.
Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.
Sacchetti A, Teeuwssen M, Verhagen M, Joosten R, Xu T, Stabile R, van der Steen B, Watson MM, Gusinac A, Kim WK, Ubink I, Van de Werken HJ, Fumagalli A, Paauwe M, Van Rheenen J, Sansom OJ, Kranenburg O, Fodde R. Sacchetti A, et al. Among authors: fumagalli a. Elife. 2021 May 26;10:e61461. doi: 10.7554/eLife.61461. Elife. 2021. PMID: 34036938 Free PMC article.
A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.
Vecchione L, Gambino V, Raaijmakers J, Schlicker A, Fumagalli A, Russo M, Villanueva A, Beerling E, Bartolini A, Mollevi DG, El-Murr N, Chiron M, Calvet L, Nicolazzi C, Combeau C, Henry C, Simon IM, Tian S, in 't Veld S, D'ario G, Mainardi S, Beijersbergen RL, Lieftink C, Linn S, Rumpf-Kienzl C, Delorenzi M, Wessels L, Salazar R, Di Nicolantonio F, Bardelli A, van Rheenen J, Medema RH, Tejpar S, Bernards R. Vecchione L, et al. Among authors: fumagalli a. Cell. 2016 Apr 7;165(2):317-30. doi: 10.1016/j.cell.2016.02.059. Cell. 2016. PMID: 27058664 Free article.
Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.
Oost KC, van Voorthuijsen L, Fumagalli A, Lindeboom RGH, Sprangers J, Omerzu M, Rodriguez-Colman MJ, Heinz MC, Verlaan-Klink I, Maurice MM, Burgering BMT, van Rheenen J, Vermeulen M, Snippert HJG. Oost KC, et al. Among authors: fumagalli a. Cell Rep. 2018 Feb 6;22(6):1600-1614. doi: 10.1016/j.celrep.2018.01.033. Cell Rep. 2018. PMID: 29425513 Free PMC article.
Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids.
Fumagalli A, Drost J, Suijkerbuijk SJ, van Boxtel R, de Ligt J, Offerhaus GJ, Begthel H, Beerling E, Tan EH, Sansom OJ, Cuppen E, Clevers H, van Rheenen J. Fumagalli A, et al. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2357-E2364. doi: 10.1073/pnas.1701219114. Epub 2017 Mar 7. Proc Natl Acad Sci U S A. 2017. PMID: 28270604 Free PMC article.
16 results