Production of Valuable Compounds and Bioactive Metabolites from By-Products of Fish Discards Using Chemical Processing, Enzymatic Hydrolysis, and Bacterial Fermentation

Mar Drugs. 2019 Feb 27;17(3):139. doi: 10.3390/md17030139.

Abstract

The objective of this report was to investigate the isolation and recovery of different biocompounds and bioproducts from wastes (skins and heads) that were obtained from five species discarded by fishing fleets (megrim, hake, boarfish, grenadier, and Atlantic horse mackerel). Based on chemical treatments, enzymatic hydrolysis, and bacterial fermentation, we have isolated and produced gelatinous solutions, oils that are rich in omega-3, fish protein hydrolysates (FPHs) with antioxidant and antihypertensive activities, and peptones. FPHs showed degrees of hydrolysis higher than 13%, with soluble protein concentrations greater than 27 g/L and in vitro digestibilities superior to 90%. Additionally, amino acids compositions were always valuable and bioactivities were, in some cases, remarkable. Peptones that were obtained from FPHs of skin and the heads were demonstrated to be a viable alternative to expensive commercial ones indicated for the production of biomass, lactic acid, and pediocin SA-1 from Pediococcus acidilactici.

Keywords: bioactivities; by-products valorization; fish discards; fish protein hydrolysates; lactic acid bacteria; marine peptones.

MeSH terms

  • Animals
  • Antihypertensive Agents / economics
  • Antihypertensive Agents / isolation & purification
  • Antihypertensive Agents / pharmacology
  • Antioxidants / economics
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology
  • Bacteria / metabolism
  • Biological Products / economics
  • Biological Products / isolation & purification*
  • Biological Products / pharmacology
  • Fatty Acids, Omega-3 / economics
  • Fatty Acids, Omega-3 / isolation & purification*
  • Fatty Acids, Omega-3 / pharmacology
  • Fermentation
  • Fisheries / economics
  • Fishes*
  • Head
  • Hydrolysis
  • Peptones / economics
  • Peptones / isolation & purification*
  • Peptones / pharmacology
  • Protein Hydrolysates / economics
  • Protein Hydrolysates / isolation & purification*
  • Protein Hydrolysates / pharmacology
  • Skin / chemistry
  • Spain

Substances

  • Antihypertensive Agents
  • Antioxidants
  • Biological Products
  • Fatty Acids, Omega-3
  • Peptones
  • Protein Hydrolysates