Biosynthesis of zinc oxide nanoparticles using leaf extracts of Alchornea laxiflora and its tyrosinase inhibition and catalytic studies

Zinc oxide nanoparticles (ZnO-NPs) were synthesized using a simple, low cost and safe method involving aqueous leaf extracts of Alchornea laxiflora and a zinc precursor salt. The nanoparticles were characterized by ultraviolet-visible (UV-vis), Fourier transform (FT-IR) spectroscopy, Energy dispersive X-ray (EDX), X-ray diffraction (XRD) and Scanning electron microscope (SEM). They were evaluated for their potentials as tyrosinase inhibitors and as catalysts in the degradation of Congo red dye. The UV-vis spectra gave characteristic surface Plasmon bands within the range 276-456 nm. The band gap energies of the ZnO-NPs were of the range, 2.50-3.67 ev. The SEM results showed average sizes of 29 nm and 38 nm for particles obtained using 1 mL and 2 mL of the plant extracts respectively. EDX plot showed the elemental compositions of the nanoparticles with zinc and oxygen being pronounced. The ZnO nanoparticles exhibited good photocatalytic efficiency of 87 % degradation of Congo red (CR) dye molecules in 60 min, They also showed good anti-tyrosinase ability with an IC50 of 66.28 μg/mL. Overall the biogenic ZnO nanoparticles are promising materials for dual applications as photocatalysts in the degradation of Congo red dye and as tyrosinase inhibitors.