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"Stapling" scFv for multispecific biotherapeutics of superior properties.
Boucher LE, Prinslow EG, Feldkamp M, Yi F, Nanjunda R, Wu SJ, Liu T, Lacy ER, Jacobs S, Kozlyuk N, Del Rosario B, Wu B, Aquino P, Davidson RC, Heyne S, Mazzanti N, Testa J, Diem MD, Gorre E, Mahan A, Nanda H, Gunawardena HP, Gervais A, Armstrong AA, Teplyakov A, Huang C, Zwolak A, Chowdhury P, Cheung WC, Luo J. Boucher LE, et al. Among authors: armstrong aa. MAbs. 2023 Jan-Dec;15(1):2195517. doi: 10.1080/19420862.2023.2195517. MAbs. 2023. PMID: 37074212 Free PMC article.
A stable, engineered TL1A ligand co-stimulates T cells via specific binding to DR3.
Zwolak A, Chan SR, Harvilla P, Mahady S, Armstrong AA, Luistro L, Tamot N, Yamada D, Derebe M, Pomerantz S, Chiu M, Ganesan R, Chowdhury P. Zwolak A, et al. Among authors: armstrong aa. Sci Rep. 2022 Nov 29;12(1):20538. doi: 10.1038/s41598-022-24984-y. Sci Rep. 2022. PMID: 36446890 Free PMC article.
14 results