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Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion.
Fan Y, Teng Y, Loison F, Pang A, Kasorn A, Shao X, Zhang C, Ren Q, Yu H, Zheng Y, Cancelas JA, Manis J, Chai L, Park SY, Zhao L, Xu Y, Feng S, Silberstein LE, Ma F, Luo HR. Fan Y, et al. Among authors: kasorn a. Sci Transl Med. 2021 Jul 28;13(604):eabb1069. doi: 10.1126/scitranslmed.abb1069. Sci Transl Med. 2021. PMID: 34321317 Free PMC article.
Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.
Hattori H, Subramanian KK, Sakai J, Jia Y, Li Y, Porter TF, Loison F, Sarraj B, Kasorn A, Jo H, Blanchard C, Zirkle D, McDonald D, Pai SY, Serhan CN, Luo HR. Hattori H, et al. Among authors: kasorn a. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3546-51. doi: 10.1073/pnas.0914351107. Epub 2010 Feb 8. Proc Natl Acad Sci U S A. 2010. PMID: 20142487 Free PMC article.