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2015 1
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Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness.
Revilla G, Pons MP, Baila-Rueda L, García-León A, Santos D, Cenarro A, Magalhaes M, Blanco RM, Moral A, Ignacio Pérez J, Sabé G, González C, Fuste V, Lerma E, Faria MDS, de Leiva A, Corcoy R, Carles Escolà-Gil J, Mato E. Revilla G, et al. Among authors: garcia leon a. Sci Rep. 2019 Jul 16;9(1):10260. doi: 10.1038/s41598-019-46727-2. Sci Rep. 2019. PMID: 31311983 Free PMC article.
Engineering non-antibody human proteins as efficient scaffolds for selective, receptor-targeted drug delivery.
Serna N, Pallarès V, Unzueta U, Garcia-Leon A, Voltà-Durán E, Sánchez-Chardi A, Parladé E, Rueda A, Casanova I, Falgàs A, Alba-Castellón L, Sierra J, Villaverde A, Vázquez E, Mangues R. Serna N, et al. Among authors: garcia leon a. J Control Release. 2022 Mar;343:277-287. doi: 10.1016/j.jconrel.2022.01.017. Epub 2022 Jan 17. J Control Release. 2022. PMID: 35051493
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.
Pallarès V, Unzueta U, Falgàs A, Aviñó A, Núñez Y, García-León A, Sánchez-García L, Serna N, Gallardo A, Alba-Castellón L, Álamo P, Sierra J, Cedó L, Eritja R, Villaverde A, Vázquez E, Casanova I, Mangues R. Pallarès V, et al. Among authors: garcia leon a. Biomaterials. 2022 Jan;280:121258. doi: 10.1016/j.biomaterials.2021.121258. Epub 2021 Nov 24. Biomaterials. 2022. PMID: 34847435 Free article.
Phytosterol-mediated inhibition of intestinal cholesterol absorption in mice is independent of liver X receptor.
Cedó L, Santos D, Ludwig IA, Silvennoinen R, García-León A, Kaipiainen L, Carbó JM, Valledor AF, Gylling H, Motilva MJ, Kovanen PT, Lee-Rueckert M, Blanco-Vaca F, Escolà-Gil JC. Cedó L, et al. Among authors: garcia leon a. Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201700055. Epub 2017 Apr 5. Mol Nutr Food Res. 2017. PMID: 28296229
A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4+ lymphoma cells without toxicity in immunocompromised and immunocompetent mice.
Falgàs A, Garcia-León A, Núñez Y, Serna N, Sánchez-Garcia L, Unzueta U, Voltà-Durán E, Aragó M, Álamo P, Alba-Castellón L, Sierra J, Gallardo A, Villaverde A, Vázquez E, Mangues R, Casanova I. Falgàs A, et al. Among authors: garcia leon a. Biomed Pharmacother. 2022 Jun;150:112940. doi: 10.1016/j.biopha.2022.112940. Epub 2022 Apr 11. Biomed Pharmacother. 2022. PMID: 35421785 Free article.
Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report.
Martínez-López D, Cedó L, Metso J, Burillo E, García-León A, Canyelles M, Lindholt JS, Torres-Fonseca M, Blanco-Colio LM, Vázquez J, Blanco-Vaca F, Jauhiainen M, Martín-Ventura JL, Escolà-Gil JC. Martínez-López D, et al. Among authors: garcia leon a. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2750-2754. doi: 10.1161/ATVBAHA.118.311704. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354236
Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis.
Fernández-de-Retana S, Cano-Sarabia M, Marazuela P, Sánchez-Quesada JL, Garcia-Leon A, Montañola A, Montaner J, Maspoch D, Hernández-Guillamon M. Fernández-de-Retana S, et al. Among authors: garcia leon a. Sci Rep. 2017 Nov 7;7(1):14637. doi: 10.1038/s41598-017-15215-w. Sci Rep. 2017. PMID: 29116115 Free PMC article.
T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo.
Núñez Y, Garcia-León A, Falgàs A, Serna N, Sánchez-García L, Garrido A, Sierra J, Gallardo A, Unzueta U, Vázquez E, Villaverde A, Mangues R, Casanova I. Núñez Y, et al. Among authors: garcia leon a. Pharmaceutics. 2023 Feb 22;15(3):727. doi: 10.3390/pharmaceutics15030727. Pharmaceutics. 2023. PMID: 36986589 Free PMC article.
13 results