Validation of a Finite Element Simulation for Predicting Individual Knee Joint Kinematics

IEEE Open J Eng Med Biol. 2023 Mar 16:5:125-132. doi: 10.1109/OJEMB.2023.3258362. eCollection 2024.

Abstract

Goal: We introduce an in-vivo validated finite element (FE) simulation approach for predicting individual knee joint kinematics. Our vision is to improve clinicians' understanding of the complex individual anatomy and potential pathologies to improve treatment and restore physiological joint kinematics. Methods: Our 3D FE modeling approach for individual human knee joints is based on segmentation of anatomical structures extracted from routine static magnetic resonance (MR) images. We validate the predictive abilities of our model using static MR images of the knees of eleven healthy volunteers in dedicated knee poses, which are achieved using a customized MR-compatible pneumatic loading device. Results: Our FE simulations reach an average translational accuracy of 2 mm and an average angular accuracy of 1[Formula: see text] compared to the reference knee pose. Conclusions: Reaching high accuracy, our individual FE model can be used in the decision-making process to restore knee joint stability and functionality after various knee injuries.

Keywords: Finite element knee joint model; joint motion prediction; model validation; pneumatic loading device; subject-specific kinematics.

Grants and funding

This work was supported by the German Ministry of Education and Research (BMBF) in the call “Individualisierte Medizintechnik” under contract 13GW0277.