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Year | Number of Results |
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2021 | 2 |
2022 | 1 |
2023 | 2 |
2024 | 0 |
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Page 1
Pyrazolidinone-based peptidomimetic SARS-CoV-2 Mpro inhibitors.
Bioorg Med Chem Lett. 2023 Nov 15;96:129530. doi: 10.1016/j.bmcl.2023.129530. Epub 2023 Oct 20.
Bioorg Med Chem Lett. 2023.
PMID: 37866713
3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors.
Bobileva O, Bobrovs R, Sirma EE, Kanepe I, Bula AL, Patetko L, Ramata-Stunda A, Grinberga S, Jirgensons A, Jaudzems K.
Bobileva O, et al. Among authors: bula al.
Molecules. 2023 Jan 12;28(2):768. doi: 10.3390/molecules28020768.
Molecules. 2023.
PMID: 36677825
Free PMC article.
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Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Berg H, Wirtz Martin MA, Altincekic N, Alshamleh I, Kaur Bains J, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C, Gande SL, Hargittay B, Hohmann KF, Hutchison MT, Marianne Korn S, Krishnathas R, Kutz F, Linhard V, Matzel T, Meiser N, Niesteruk A, Pyper DJ, Schulte L, Trucks S, Azzaoui K, Blommers MJJ, Gadiya Y, Karki R, Zaliani A, Gribbon P, da Silva Almeida M, Dinis Anobom C, Bula AL, Bütikofer M, Putinhon Caruso Í, Caterina Felli I, Da Poian AT, Cardoso de Amorim G, Fourkiotis NK, Gallo A, Ghosh D, Gomes-Neto F, Gorbatyuk O, Hao B, Kurauskas V, Lecoq L, Li Y, Cunha Mebus-Antunes N, Mompeán M, Cristtina Neves-Martins T, Ninot-Pedrosa M, Pinheiro AS, Pontoriero L, Pustovalova Y, Riek R, Robertson AJ, Jose Abi Saad M, Treviño MÁ, Tsika AC, Almeida FCL, Bax A, Henzler-Wildman K, Hoch JC, Jaudzems K, Laurents DV, Orts J, Pierattelli R, Spyroulias GA, Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Löhr F, Qureshi N, Richter C, Saxena K, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H.
Berg H, et al. Among authors: bula al.
Angew Chem Int Ed Engl. 2022 Nov 14;61(46):e202205858. doi: 10.1002/anie.202205858. Epub 2022 Oct 13.
Angew Chem Int Ed Engl. 2022.
PMID: 36115062
Free PMC article.
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Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening.
Bobrovs R, Kanepe I, Narvaiss N, Patetko L, Kalnins G, Sisovs M, Bula AL, Grinberga S, Boroduskis M, Ramata-Stunda A, Rostoks N, Jirgensons A, Tars K, Jaudzems K.
Bobrovs R, et al. Among authors: bula al.
Pharmaceuticals (Basel). 2021 Nov 30;14(12):1243. doi: 10.3390/ph14121243.
Pharmaceuticals (Basel). 2021.
PMID: 34959647
Free PMC article.
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Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate.
Bobiļeva O, Bobrovs R, Kaņepe I, Patetko L, Kalniņš G, Šišovs M, Bula AL, Gri Nberga S, Borodušķis MR, Ramata-Stunda A, Rostoks N, Jirgensons A, Ta Rs K, Jaudzems K.
Bobiļeva O, et al. Among authors: bula al.
ACS Med Chem Lett. 2021 Jun 9;12(7):1102-1107. doi: 10.1021/acsmedchemlett.1c00140. eCollection 2021 Jul 8.
ACS Med Chem Lett. 2021.
PMID: 34257831
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