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MED12 mutations and fumarate hydratase inactivation in uterine adenomyomas.
Heikkinen T, Äyräväinen A, Hänninen J, Ahvenainen T, Bützow R, Pasanen A, Vahteristo P. Heikkinen T, et al. Among authors: ayravainen a. Hum Reprod Open. 2018 Nov 17;2018(4):hoy020. doi: 10.1093/hropen/hoy020. eCollection 2018. Hum Reprod Open. 2018. PMID: 30895261 Free PMC article.
A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase.
Mehine M, Ahvenainen T, Khamaiseh S, Härkönen J, Reinikka S, Heikkinen T, Äyräväinen A, Pakarinen P, Härkki P, Pasanen A, Levonen AL, Bützow R, Vahteristo P. Mehine M, et al. Among authors: ayravainen a. Oncogenesis. 2022 Sep 7;11(1):52. doi: 10.1038/s41389-022-00425-3. Oncogenesis. 2022. PMID: 36068196 Free PMC article.
3'RNA and whole-genome sequencing of archival uterine leiomyomas reveal a tumor subtype with chromosomal rearrangements affecting either HMGA2, HMGA1, or PLAG1.
Jokinen V, Mehine M, Reinikka S, Khamaiseh S, Ahvenainen T, Äyräväinen A, Härkki P, Bützow R, Pasanen A, Vahteristo P. Jokinen V, et al. Among authors: ayravainen a. Genes Chromosomes Cancer. 2023 Jan;62(1):27-38. doi: 10.1002/gcc.23088. Epub 2022 Aug 1. Genes Chromosomes Cancer. 2023. PMID: 35822448 Free PMC article.