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Broad Spectrum β-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate.
ACS Infect Dis. 2020 Jun 12;6(6):1398-1404. doi: 10.1021/acsinfecdis.9b00330. Epub 2020 Jan 6.
ACS Infect Dis. 2020.
PMID: 31841636
Faropenem reacts with serine and metallo-β-lactamases to give multiple products.
Lucic A, Hinchliffe P, Malla TR, Tooke CL, Brem J, Calvopiña K, Lohans CT, Rabe P, McDonough MA, Armistead T, Orville AM, Spencer J, Schofield CJ.
Lucic A, et al.
Eur J Med Chem. 2021 Apr 5;215:113257. doi: 10.1016/j.ejmech.2021.113257. Epub 2021 Feb 9.
Eur J Med Chem. 2021.
PMID: 33618159
Free PMC article.
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Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2.
Lucic A, Malla TR, Calvopiña K, Tooke CL, Brem J, McDonough MA, Spencer J, Schofield CJ.
Lucic A, et al.
Antibiotics (Basel). 2022 Mar 16;11(3):396. doi: 10.3390/antibiotics11030396.
Antibiotics (Basel). 2022.
PMID: 35326858
Free PMC article.
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