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Small molecule targeting of SHIP1 and SHIP2.
Kerr WG, Pedicone C, Dormann S, Pacherille A, Chisholm JD. Kerr WG, et al. Among authors: pacherille a. Biochem Soc Trans. 2020 Feb 28;48(1):291-300. doi: 10.1042/BST20190775. Biochem Soc Trans. 2020. PMID: 32049315 Review.
SHIP inhibition mediates select TREM2-induced microglial functions.
Ramakrishnan GS, Berry WL, Pacherille A, Kerr WG, Chisholm JD, Pedicone C, Humphrey MB. Ramakrishnan GS, et al. Among authors: pacherille a. Mol Immunol. 2024 Jun;170:35-45. doi: 10.1016/j.molimm.2024.04.002. Epub 2024 Apr 12. Mol Immunol. 2024. PMID: 38613944 Free article.
Structure-Activity Studies on Bis-Sulfonamide SHIP1 Activators.
Meyer ST, Fernandes S, Anderson RE, Pacherille A, Toms B, Kerr WG, Chisholm JD. Meyer ST, et al. Among authors: pacherille a. Molecules. 2023 Dec 12;28(24):8048. doi: 10.3390/molecules28248048. Molecules. 2023. PMID: 38138538 Free PMC article.