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PNPLA3 I148M (rs738409) genetic variant and age at onset of at-risk alcohol consumption are independent risk factors for alcoholic cirrhosis.
Burza MA, Molinaro A, Attilia ML, Rotondo C, Attilia F, Ceccanti M, Ferri F, Maldarelli F, Maffongelli A, De Santis A, Attili AF, Romeo S, Ginanni Corradini S. Burza MA, et al. Among authors: maffongelli a. Liver Int. 2014 Apr;34(4):514-20. doi: 10.1111/liv.12310. Epub 2013 Sep 19. Liver Int. 2014. PMID: 24102786 Free PMC article.
A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption.
Mancina RM, Ferri F, Farcomeni A, Molinaro A, Maffongelli A, Mischitelli M, Poli E, Parlati L, Burza MA, De Santis A, Attilia F, Rotondo C, Rando MM, Attilia ML, Ceccanti M, Ginanni Corradini S. Mancina RM, et al. Among authors: maffongelli a. Appl Clin Genet. 2019 Jan 10;12:1-10. doi: 10.2147/TACG.S187922. eCollection 2019. Appl Clin Genet. 2019. PMID: 30666147 Free PMC article.