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Synthetic Approaches to Mono- and Bicyclic Perortho-Esters with a Central 1,2,4-Trioxane Ring as the Privileged Lead Structure in Antimalarial and Antitumor-Active Peroxides and Clarification of the Peroxide Relevance.
Molecules. 2017 Jan 11;22(1):119. doi: 10.3390/molecules22010119.
Molecules. 2017.
PMID: 28085079
Free PMC article.
Bicyclic peroxides and perorthoesters with 1,2,4-trioxane structures.
Griesbeck AG, Blunk D, El-Idreesy TT, Raabe A.
Griesbeck AG, et al. Among authors: raabe a.
Angew Chem Int Ed Engl. 2007;46(46):8883-6. doi: 10.1002/anie.200701397.
Angew Chem Int Ed Engl. 2007.
PMID: 17943925
No abstract available.
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Antimalarial peroxide dyads from natural artemisinin and hydroxyalkylated 1,2,4-trioxanes.
Griesbeck AG, Neudörfl J, Hörauf A, Specht S, Raabe A.
Griesbeck AG, et al. Among authors: raabe a.
J Med Chem. 2009 May 28;52(10):3420-3. doi: 10.1021/jm9002523.
J Med Chem. 2009.
PMID: 19402629
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