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Page 1
Perspectives on the Designation of Oligonucleotide Starting Materials.
Nucleic Acid Ther. 2021 Apr;31(2):93-113. doi: 10.1089/nat.2020.0909. Epub 2021 Feb 2.
Nucleic Acid Ther. 2021.
PMID: 33534646
Free PMC article.
Impurity Qualification Toxicology Study for a 2'-O-Methoxyethyl-Modified Antisense Inhibitor in Mice.
Kim TW, Papagiannis C, Capaldi D, McPherson AK, Mahdi F, Luu N, Rodriguez AA, Hoffmaster C, Serota D, Henry SP.
Kim TW, et al. Among authors: mcpherson ak.
Nucleic Acid Ther. 2020 Feb;30(1):14-21. doi: 10.1089/nat.2019.0780. Epub 2019 Nov 5.
Nucleic Acid Ther. 2020.
PMID: 31687889
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Synthesis of 5'-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies.
Cedillo I, Chreng D, Engle E, Chen L, McPherson AK, Rodriguez AA.
Cedillo I, et al. Among authors: mcpherson ak.
Molecules. 2017 Aug 15;22(8):1356. doi: 10.3390/molecules22081356.
Molecules. 2017.
PMID: 28809818
Free PMC article.
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Formation of the N(2)-acetyl-2,6-diaminopurine oligonucleotide impurity caused by acetyl capping.
Rodriguez AA, Cedillo I, Mowery BP, Gaus HJ, Krishnamoorthy SS, McPherson AK.
Rodriguez AA, et al. Among authors: mcpherson ak.
Bioorg Med Chem Lett. 2014 Aug 1;24(15):3243-6. doi: 10.1016/j.bmcl.2014.06.025. Epub 2014 Jun 18.
Bioorg Med Chem Lett. 2014.
PMID: 24980055
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Conversion of adenine to 5-amino-4-pyrimidinylimidazole caused by acetyl capping during solid phase oligonucleotide synthesis.
Rodriguez AA, Cedillo I, McPherson AK.
Rodriguez AA, et al. Among authors: mcpherson ak.
Bioorg Med Chem Lett. 2016 Aug 1;26(15):3468-71. doi: 10.1016/j.bmcl.2016.06.042. Epub 2016 Jun 18.
Bioorg Med Chem Lett. 2016.
PMID: 27353533
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