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2014 | 1 |
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Page 1
Impurity Qualification Toxicology Study for a 2'-O-Methoxyethyl-Modified Antisense Inhibitor in Mice.
Nucleic Acid Ther. 2020 Feb;30(1):14-21. doi: 10.1089/nat.2019.0780. Epub 2019 Nov 5.
Nucleic Acid Ther. 2020.
PMID: 31687889
Synthesis of 5'-GalNAc-Conjugated Oligonucleotides: A Comparison of Solid and Solution-Phase Conjugation Strategies.
Cedillo I, Chreng D, Engle E, Chen L, McPherson AK, Rodriguez AA.
Cedillo I, et al. Among authors: rodriguez aa.
Molecules. 2017 Aug 15;22(8):1356. doi: 10.3390/molecules22081356.
Molecules. 2017.
PMID: 28809818
Free PMC article.
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Formation of the N(2)-acetyl-2,6-diaminopurine oligonucleotide impurity caused by acetyl capping.
Rodriguez AA, Cedillo I, Mowery BP, Gaus HJ, Krishnamoorthy SS, McPherson AK.
Rodriguez AA, et al.
Bioorg Med Chem Lett. 2014 Aug 1;24(15):3243-6. doi: 10.1016/j.bmcl.2014.06.025. Epub 2014 Jun 18.
Bioorg Med Chem Lett. 2014.
PMID: 24980055
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Conversion of adenine to 5-amino-4-pyrimidinylimidazole caused by acetyl capping during solid phase oligonucleotide synthesis.
Rodriguez AA, Cedillo I, McPherson AK.
Rodriguez AA, et al.
Bioorg Med Chem Lett. 2016 Aug 1;26(15):3468-71. doi: 10.1016/j.bmcl.2016.06.042. Epub 2016 Jun 18.
Bioorg Med Chem Lett. 2016.
PMID: 27353533
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Determination of individual oligonucleotide impurities by small amine ion pair-RP HPLC MS and MS/MS: n - 1 impurities.
Roussis SG, Rodriguez AA, Rentel C.
Roussis SG, et al. Among authors: rodriguez aa.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Apr 15;1169:122611. doi: 10.1016/j.jchromb.2021.122611. Epub 2021 Mar 1.
J Chromatogr B Analyt Technol Biomed Life Sci. 2021.
PMID: 33706187
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New Architectures in Hydrogen Bond Catalysis.
Rodriguez AA, Yoo H, Ziller JW, Shea KJ.
Rodriguez AA, et al.
Tetrahedron Lett. 2009 Dec 9;50(49):6830-6833. doi: 10.1016/j.tetlet.2009.09.129.
Tetrahedron Lett. 2009.
PMID: 20160884
Free PMC article.
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Asymmetric bisboranes as bidentate catalysts for carbonyl substrates.
Rodriguez AA, Zhao C, Shea KJ.
Rodriguez AA, et al.
Org Lett. 2009 Feb 5;11(3):713-5. doi: 10.1021/ol802793k.
Org Lett. 2009.
PMID: 19175350
Free PMC article.
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