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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 2
2006 2
2007 1
2008 2
2009 1
2013 4
2014 2
2016 2
2017 4
2018 3
2019 4
2020 4
2021 6
2022 3
2023 2
2024 1

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36 results

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Page 1
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
Sellmayr M, Hernandez Petzsche MR, Ma Q, Krüger N, Liapis H, Brink A, Lenz B, Angelotti ML, Gnemmi V, Kuppe C, Kim H, Bindels EMJ, Tajti F, Saez-Rodriguez J, Lech M, Kramann R, Romagnani P, Anders HJ, Steiger S. Sellmayr M, et al. Among authors: brink a. J Am Soc Nephrol. 2020 Dec;31(12):2773-2792. doi: 10.1681/ASN.2020040523. Epub 2020 Sep 16. J Am Soc Nephrol. 2020. PMID: 32938648 Free PMC article.
Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier Risdiplam.
Fowler S, Brink A, Cleary Y, Günther A, Heinig K, Husser C, Kletzl H, Kratochwil N, Mueller L, Savage M, Stillhart C, Tuerck D, Ullah M, Umehara K, Poirier A. Fowler S, et al. Among authors: brink a. Drug Metab Dispos. 2022 Jan;50(1):65-75. doi: 10.1124/dmd.121.000563. Epub 2021 Oct 7. Drug Metab Dispos. 2022. PMID: 34620695 Review.
Qualification of impurities based on metabolite data.
Weidolf L, Andersson T, Bercu JP, Brink A, Glowienke S, Harvey J, Hayes MA, Jacques P, Lu C, Manevski N, Muster W, Nudelman R, Ogilvie R, Ottosson J, Teasdale A, Trela B. Weidolf L, et al. Among authors: brink a. Regul Toxicol Pharmacol. 2020 Feb;110:104524. doi: 10.1016/j.yrtph.2019.104524. Epub 2019 Nov 14. Regul Toxicol Pharmacol. 2020. PMID: 31734179
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Duschmalé J, Schäublin A, Funder E, Schmidt S, Kiełpiński ŁJ, Nymark H, Jensen K, Koch T, Duschmalé M, Koller E, Møller MR, Schadt S, Husser C, Brink A, Sewing S, Minz T, Wengel J, Bleicher K, Li M. Duschmalé J, et al. Among authors: brink a. Mol Ther Nucleic Acids. 2022 Jun 22;29:176-188. doi: 10.1016/j.omtn.2022.06.010. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 35860384 Free PMC article.
Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.
Zeller A, Brigo A, Brink A, Guerard M, Lang D, Muster W, Runge F, Sutter A, Vock E, Wichard J, Schadt S. Zeller A, et al. Among authors: brink a. Chem Res Toxicol. 2020 Jan 21;33(1):10-19. doi: 10.1021/acs.chemrestox.9b00348. Epub 2020 Jan 9. Chem Res Toxicol. 2020. PMID: 31859487
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats.
Romero-Palomo F, Festag M, Lenz B, Schadt S, Brink A, Kipar A, Steinhuber B, Husser C, Koller E, Sewing S, Tessier Y, Dzygiel P, Fischer G, Winter M, Hetzel U, Mihatsch MJ, Braendli-Baiocco A. Romero-Palomo F, et al. Among authors: brink a. Toxicol Pathol. 2021 Aug;49(6):1174-1192. doi: 10.1177/01926233211011615. Epub 2021 Jun 1. Toxicol Pathol. 2021. PMID: 34060347
In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK).
Meneses-Lorente G, Fowler S, Guerini E, Kowalski K, Chow-Maneval E, Yu L, Mercier F, Ullah M, Umehara K, Brink A, Buchheit V, Zwanziger E, Phipps A, Djebli N. Meneses-Lorente G, et al. Among authors: brink a. Invest New Drugs. 2022 Feb;40(1):68-80. doi: 10.1007/s10637-021-01156-9. Epub 2021 Aug 21. Invest New Drugs. 2022. PMID: 34417912 Free PMC article.
36 results