Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 2
1982 1
1983 2
1985 1
1987 3
1988 1
1989 3
1990 10
1991 5
1992 3
1993 7
1994 7
1995 3
1996 9
1997 11
1998 14
1999 13
2000 13
2001 21
2002 22
2003 13
2004 13
2005 13
2006 7
2007 8
2008 7
2009 9
2010 5
2011 9
2012 11
2013 8
2014 15
2015 23
2016 24
2017 13
2018 17
2019 11
2020 23
2021 18
2022 14
2023 7
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

393 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for andrea clone
Your search for Andrea Celone retrieved no results
The β-Secretase BACE1 in Alzheimer's Disease.
Hampel H, Vassar R, De Strooper B, Hardy J, Willem M, Singh N, Zhou J, Yan R, Vanmechelen E, De Vos A, Nisticò R, Corbo M, Imbimbo BP, Streffer J, Voytyuk I, Timmers M, Tahami Monfared AA, Irizarry M, Albala B, Koyama A, Watanabe N, Kimura T, Yarenis L, Lista S, Kramer L, Vergallo A. Hampel H, et al. Biol Psychiatry. 2021 Apr 15;89(8):745-756. doi: 10.1016/j.biopsych.2020.02.001. Epub 2020 Feb 13. Biol Psychiatry. 2021. PMID: 32223911 Free PMC article. Review.
BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) was initially cloned and characterized in 1999. It is required for the generation of all monomeric forms of amyloid-beta (Abeta), including Abeta(42), which aggregates into bioactive conformational species and l …
BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) was initially cloned and characterized in 1999. It is required for the …
Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review-Part II.
Viaggi B, Cangialosi A, Langer M, Olivieri C, Gori A, Corona A, Finazzi S, Di Paolo A. Viaggi B, et al. Antibiotics (Basel). 2022 Sep 3;11(9):1193. doi: 10.3390/antibiotics11091193. Antibiotics (Basel). 2022. PMID: 36139972 Free PMC article. Review.
Antimicrobials may be used in off-label regimens to maximize the probability of therapeutic concentrations within infected tissues and to prevent the selection of resistant clones. Interestingly, the literature clearly shows that the rate of tissue penetration is variable …
Antimicrobials may be used in off-label regimens to maximize the probability of therapeutic concentrations within infected tissues and to pr …
The co-evolution of the genome and epigenome in colorectal cancer.
Heide T, Househam J, Cresswell GD, Spiteri I, Lynn C, Mossner M, Kimberley C, Fernandez-Mateos J, Chen B, Zapata L, James C, Barozzi I, Chkhaidze K, Nichol D, Gunasri V, Berner A, Schmidt M, Lakatos E, Baker AM, Costa H, Mitchinson M, Piazza R, Jansen M, Caravagna G, Ramazzotti D, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Graham TA, Sottoriva A. Heide T, et al. Nature. 2022 Nov;611(7937):733-743. doi: 10.1038/s41586-022-05202-1. Epub 2022 Oct 26. Nature. 2022. PMID: 36289335 Free PMC article.
Here we investigate the co-evolution of the genome and epigenome of colorectal tumours at single-clone resolution using spatial multi-omic profiling of individual glands. ...
Here we investigate the co-evolution of the genome and epigenome of colorectal tumours at single-clone resolution using spatial multi …
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
Consistently, computational inference on the spatial patterning of tumour phylogenies finds that a considerable proportion of CRCs did not show evidence of subclonal selection, with only a subset of putative genetic drivers associated with subclone expansions. Spatial intermixing …
Consistently, computational inference on the spatial patterning of tumour phylogenies finds that a considerable proportion of CRCs did not s …
Mobius Assembly.
Andreou AI, Nakayama N. Andreou AI, et al. Methods Mol Biol. 2020;2205:201-218. doi: 10.1007/978-1-0716-0908-8_12. Methods Mol Biol. 2020. PMID: 32809201
Mobius Assembly is a versatile and user-friendly DNA Assembly method, which facilitates rapid and simple generation of DNA constructs. Mobius Assembly combines high cloning capacity and vector toolkit simplicity to streamline combinatorial assemblies. It is a two-level hie …
Mobius Assembly is a versatile and user-friendly DNA Assembly method, which facilitates rapid and simple generation of DNA constructs. Mobiu …
Venetoclax and idasanutlin in relapsed/refractory AML: a nonrandomized, open-label phase 1b trial.
Daver NG, Dail M, Garcia JS, Jonas BA, Yee KWL, Kelly KR, Vey N, Assouline S, Roboz GJ, Paolini S, Pollyea DA, Tafuri A, Brandwein JM, Pigneux A, Powell BL, Fenaux P, Olin RL, Visani G, Martinelli G, Onishi M, Wang J, Huang W, Green C, Ott MG, Hong WJ, Konopleva MY, Andreeff M. Daver NG, et al. Blood. 2023 Mar 16;141(11):1265-1276. doi: 10.1182/blood.2022016362. Blood. 2023. PMID: 36265087 Free PMC article. Clinical Trial.
IDH1/2 and RUNX1 mutations were associated with venetoclax-idasanutlin sensitivity, even in some patients with co-occurring TP53 mutations; most emergent TP53 clones were preexisting. Our findings will aid ongoing/future trials of BCL-2/MDM2 inhibitor combinations. ...
IDH1/2 and RUNX1 mutations were associated with venetoclax-idasanutlin sensitivity, even in some patients with co-occurring TP53 mutations; …
Lysosomal alpha-mannosidase and alpha-mannosidosis.
Paciotti S, Codini M, Tasegian A, Ceccarini MR, Cataldi S, Arcuri C, Fioretti B, Albi E, Beccari T. Paciotti S, et al. Front Biosci (Landmark Ed). 2017 Jan 1;22(1):157-167. doi: 10.2741/4478. Front Biosci (Landmark Ed). 2017. PMID: 27814608 Free article. Review.
To develop this strategy a mouse model for alpha-mannosidosis has been generated and a recombinant human alpha-mannosidase has been produced from Chinese-hamster ovary cells. Interestingly it has been shown that the recombinant enzyme, used in high dose, can cross the bloo …
To develop this strategy a mouse model for alpha-mannosidosis has been generated and a recombinant human alpha-mannosidase has been produced …
Recent Advances with ER Targeted Intrabodies.
Marschall AL, Dübel S, Böldicke T. Marschall AL, et al. Adv Exp Med Biol. 2016;917:77-93. doi: 10.1007/978-3-319-32805-8_5. Adv Exp Med Biol. 2016. PMID: 27236553 Review.
ER intrabodies are recombinant antibody fragments produced and retained in the endoplasmatic reticulum (ER) of a cell or an organism with the purpose to induce phenotypes generated by interfering with the intracellular processing or by changing the location of the recogniz …
ER intrabodies are recombinant antibody fragments produced and retained in the endoplasmatic reticulum (ER) of a cell or an organism …
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors.
Zapata L, Caravagna G, Williams MJ, Lakatos E, AbdulJabbar K, Werner B, Chowell D, James C, Gourmet L, Milite S, Acar A, Riaz N, Chan TA, Graham TA, Sottoriva A. Zapata L, et al. Nat Genet. 2023 Mar;55(3):451-460. doi: 10.1038/s41588-023-01313-1. Epub 2023 Mar 9. Nat Genet. 2023. PMID: 36894710 Free PMC article.
In cancer, evolutionary forces select for clones that evade the immune system. Here we analyzed >10,000 primary tumors and 356 immune-checkpoint-treated metastases using immune dN/dS, the ratio of nonsynonymous to synonymous mutations in the immunopeptidome, to measure …
In cancer, evolutionary forces select for clones that evade the immune system. Here we analyzed >10,000 primary tumors and 356 imm …
IgG-Fc glycoengineering in non-mammalian expression hosts.
Loos A, Steinkellner H. Loos A, et al. Arch Biochem Biophys. 2012 Oct 15;526(2):167-73. doi: 10.1016/j.abb.2012.05.011. Epub 2012 May 23. Arch Biochem Biophys. 2012. PMID: 22634260 Free PMC article. Review.
In this review we focus on efforts towards a targeted manipulation of IgG-Fc N-glycans using non-mammalian expression hosts, i.e. yeast, insect cells and plants. Current achievements in generating human-like N-glycan structures will be presented and recent data on the mole …
In this review we focus on efforts towards a targeted manipulation of IgG-Fc N-glycans using non-mammalian expression hosts, i.e. yeast, ins …
393 results